Actively Recruiting

Age: 18Years +
All Genders
NCT04706234

Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases

Led by Kliniken Beelitz GmbH · Updated on 2025-04-09

350

Participants Needed

16

Research Sites

569 weeks

Total Duration

On this page

Sponsors

K

Kliniken Beelitz GmbH

Lead Sponsor

U

University Hospital Muenster

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a non-interventional observational study designed to systematically record the results of routine laryngeal examinations and specific characteristics of dysphagia in patients with neurodegenerative disorders. The results of a fiberoptic / flexible endoscopic evaluation of swallowing (FEES) while performing a structured task protocol will be recorded. If available, laryngeal electromyography (EMG) results will also be recorded. In addition to the examination results, demographic and disease-specific data are collected, and two questionnaires, the Swallowing Disturbance Questionnaire for Parkinson's Disease (SDQ-PD) and the swallowing specific Quality Of Life Questionnaire (SWALQOL), are administered.

CONDITIONS

Official Title

Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of probable or possible multiple system atrophy based on current consensus criteria
  • Diagnosis of probable or possible progressive supranuclear palsy according to Movement Disorders Society criteria
  • Diagnosis of Parkinson's disease based on Movement Disorders Society criteria
  • Hoehn and Yahr Stage between I and V
  • Diagnosis of motor neurone disease
  • Diagnosis of another neurodegenerative disease
  • Completed laryngopharyngeal assessment using the standardized FEES task protocol
Not Eligible

You will not qualify if you...

  • Not signing the consent form

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 16 locations

1

Department of Neurology and Department of ENT, Medical University Innsbruck

Innsbruck, Tyrol, Austria, 6020

Actively Recruiting

2

Department of Neurology, Medical University of Ulm

Ulm, Baden-Wurttemberg, Germany, 89081

Actively Recruiting

3

Movement Disorders Hospital - Kliniken Beelitz

Beelitz-Heilstätten, Brandenburg, Germany, 14547

Actively Recruiting

4

Department of Neurology, Medical School Hannover

Hanover, Lower Saxony, Germany, 30625

Actively Recruiting

5

Department of Neurology, University Hospital Münster

Münster, North Rhine-Westphalia, Germany, 48149

Actively Recruiting

6

Department of Neurology, University Hospital Carl Gustav Carus

Dresden, Saxony, Germany, 01307

Actively Recruiting

7

Department of Neueology Asklepios Klinik Stadtroda

Stadtroda, Thuringia, Germany, 07646

Actively Recruiting

8

Asklepios Fachklinikum Stadtroda

Stadtroda, Thuringia, Germany

Actively Recruiting

9

Asklepios Klinik Barmbek

Hamburg, Germany, 22291

Actively Recruiting

10

Department of Neurology Asklepios Klinik Barmbek

Hamburg, Germany, 22307

Actively Recruiting

11

Department of Neurology, Movement Disorders Unit, Medical Center Tel Aviv

Tel Aviv, Israel, 64239

Actively Recruiting

12

IRCCS Istituto delle Scienze Neurologiche, Azienda USL di Bologna

Bologna, Italy, 40124

Actively Recruiting

13

Department of Neurology, Gifu University Graduate School of Medicine

Gifu, Japan, 501-1194

Actively Recruiting

14

Department of Neurology, Medical University Warsaw

Warsaw, Poland, 02-091

Actively Recruiting

15

Department of Neurology SNUCM

Seoul, South Korea

Actively Recruiting

16

Unidad de Parkinson y Trastornos del Movimiento Instituto Clínic de Neurociencias, Hospital Clinic de Barcelona

Barcelona, Catalonia, Spain, 08036

Actively Recruiting

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Research Team

F

Florin Gandor, MD

CONTACT

T

Tobias Warnecke, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

5

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