Pilot Study of Adding Abdominal CT Scan to Lung Cancer Screening for High-Risk Smokers Aged 55 to 70

What this Trial Is About

Researchers are evaluating the addition of an abdominal CT scan to the existing Lung Cancer Screening LCS program for people aged 55 to 70 who have ever smoked. This study aims to see if mentioning the abdominal scan in the initial LCS invitation affects participation, test new ways to add the abdominal scan without causing delays, and assess if participants can be assigned to different scan groups using cluster randomisation. The research focuses on the feasibility and acceptability of combining these scans in lung cancer screening centers in Yorkshire. Participants will be invited to the NHS Lung Cancer Screening via letter or text message. Those at high risk for lung cancer based on risk models will be offered a lung scan, and some will be invited to have an abdominal CT scan at the same time. The study compares groups receiving the standard invitation with those also informed about the possible abdominal scan and evaluates the impact on scheduling and participant experience. This approach includes two study arms for invitation and scan procedures. During the study, participants attendance at screening assessments will be tracked along with the time taken for additional tasks related to the abdominal scan. Satisfaction with the scanning experience will be measured, and uptake of the abdominal scan offer will be recorded. Follow-up will occur up to six months after invitation, and data will be collected on the process and impact of adding the abdominal scan alongside lung screening. Participants will be monitored for safety and acceptability throughout the study period.

Targeted Abdominal CT in Conjunction With Lung Cancer Screening