Actively Recruiting

Age: 18Years +
All Genders
ID04246463

A Global Post Market Evaluation of Terumo Aortic Endovascular Grafts

Led by Vascutek Ltd. · Updated on 2026-03-13

1000

Participants Needed

58

Research Sites

52 weeks

Total Duration

On this page

Sponsors

V

Vascutek Ltd.

Lead Sponsor

B

Bolton Medical

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are observing the safety and performance of Terumo Aortic endovascular grafts used to treat patients with aortic aneurysms and other related conditions during routine clinical practice. This global, multi-center registry collects real-world data to better understand outcomes after these devices have been approved and are in use. The study is open label and includes multiple groups based on the type of aneurysm or device implanted. Participants receive one of several types of Terumo Aortic endovascular stent-grafts, including Thoracic Relay stent grafts, Abdominal Anaconda or Treo grafts, custom fenestrated devices, and Iliac artery-specific implants. These devices are CE marked or custom-made and are implanted following standard clinical procedures. The registry tracks patients treated with these devices in usual care settings without altering treatment. During the study, participants will attend follow-up visits where researchers collect safety data, patient-reported outcomes, and health economic information. Key outcomes measured include aortic-related mortality within 30 days post-implant, technical success on the day of surgery, and composite clinical success and additional endpoints at one year. The registry aims to monitor long-term performance and safety of these grafts in real-world use, with participation lasting as determined by follow-up schedules.

CONDITIONS

Brief Title

Terumo Aortic Global Endovascular Registry

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Minimum age as per local regulations
  • Indication for aortic endovascular repair with an approved or custom Terumo Aortic graft
  • Ability to provide informed consent
  • Emergent cases allowed if consent is obtained after intervention or by Legally Authorized Representative
  • Willingness to comply with the registry protocol
  • Willingness to attend follow-up visits
  • Patients in the TREO registry may have data migrated with approval and reconsent
Not Eligible

You will not qualify if you...

  • Unable or unwilling to comply with study follow-up
  • Contraindicated per device instructions for use
  • Any medical, social, or psychological problem preventing treatment or study procedures as judged by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Day 0

Participants receive an implant of a Terumo Aortic endovascular stent-graft device as part of standard clinical practice.

1 visit (in-person) for the implant procedure

Long-term Monitoring

Duration - Up to 1 year or longer

Participants are observed for safety, device performance, and clinical outcomes after the implant.

Follow-up visits as per routine clinical care, typically including visits at 30 days and 1 year post-implant

Trial Site Locations

Total: 58 locations

1

Long Beach Memorial Medical Center

Long Beach, California, United States, 90806

Actively Recruiting

2

University of Colorado Anschutz Medical Campus

Aurora, Colorado, United States, 80045

Actively Recruiting

3

UC Health Memorial Hospital Center

Colorado Springs, Colorado, United States, 80909

Actively Recruiting

4

Yale University

New Haven, Connecticut, United States, 06520

Actively Recruiting

5

MedStar Washington Hospital Center

Washington D.C., District of Columbia, United States, 20010

Actively Recruiting

6

University of Florida

Gainesville, Florida, United States, 32610

Actively Recruiting

7

Loyola University of Chicago (Loyola)

Chicago, Illinois, United States, 60153

Actively Recruiting

8

Ascension St. Vincent Heart Center

Indianapolis, Indiana, United States, 46260

Actively Recruiting

9

University of Michigan

Ann Arbor, Michigan, United States, 48109

Actively Recruiting

10

Cooper University Hospital

Camden, New Jersey, United States, 08103

Actively Recruiting

11

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

12

University of Pittsburgh

Pittsburgh, Pennsylvania, United States, 15232

Actively Recruiting

13

Ascension Texas Cardiovascular / UT Dell Medical School

Austin, Texas, United States, 78705

Actively Recruiting

14

Baylor, Scott & White Health (BSW Health)

Texas City, Texas, United States, 75093

Actively Recruiting

15

University of Utah

Salt Lake City, Utah, United States, 84132

Actively Recruiting

16

University of Virgina

Charlottesville, Virginia, United States, 22908

Actively Recruiting

17

Sentara Heart Hospital

Norfolk, Virginia, United States, 22042

Actively Recruiting

18

Imeldaziekenhuis

Bonheiden, Belgium

Actively Recruiting

19

Clinques Uni. St Lucs

Brussels, Belgium

Withdrawn

20

Hôpital Pneumologique et Cardiovasculaire Louis-Pradel

Bron, France

Actively Recruiting

21

CHU St Etienne

Saint-Etienne, France

Actively Recruiting

22

Klinikum Augsburg

Augsburg, Germany

Actively Recruiting

23

Evangelisches Krankenhaus Hubertus

Berlin, Germany

Actively Recruiting

24

Klinikum Chemnitz

Chemnitz, Germany

Actively Recruiting

25

University Heart Center Freiburg

Freiburg im Breisgau, Germany

Actively Recruiting

26

Aortic Center University Hospital

Göttingen, Germany

Withdrawn

27

Bonifatius Hospital

Lingen, Germany

Actively Recruiting

28

St. Franziskus Hospital

Münster, Germany

Actively Recruiting

29

University Hospital Tübingen

Tübingen, Germany

Actively Recruiting

30

Policlinico Consorziale di Bari

Bari, Italy

Actively Recruiting

31

Compensorio Sanitario Bolzano

Bolzano, Italy

Actively Recruiting

32

Cagliari-Ospedale Brotzu

Cagliari, Italy

Actively Recruiting

33

Firenze Ospedale Careggi

Careggi, Italy

Actively Recruiting

34

Azienda Ospedaliera di Catania

Catania, Italy

Actively Recruiting

35

Uni. di Modena

Modena, Italy

Not Yet Recruiting

36

Azienda Ospedaliera Universitaria Senese

Siena, Italy

Actively Recruiting

37

Maurizano Torino (turin)

Turin, Italy

Actively Recruiting

38

Turin Uni. Hospital

Turin, Italy

Not Yet Recruiting

39

Vumc Amsterdam

Amsterdam, Netherlands

Actively Recruiting

40

Rijnstate Arnham

Arnhem, Netherlands

Actively Recruiting

41

Medisch Spectrum Twente

Enschede, Netherlands

Actively Recruiting

42

UMC Gronigen

Groningen, Netherlands

Actively Recruiting

43

St. Antonius Ziekenhuis

Nieuwegein, Netherlands, 3430

Not Yet Recruiting

44

Erasmus University Medical Center

Rotterdam, Netherlands

Actively Recruiting

45

Diakonessenhuis

Utrecht, Netherlands

Actively Recruiting

46

Centro Hospital Uni Lisboa Norte

Lisbon, Portugal

Actively Recruiting

47

Hospital de Santa Marta

Lisbon, Portugal

Actively Recruiting

48

CHU Sao Joao

Porto, Portugal

Withdrawn

49

Hospital Universitari Germans

Badalona, Spain

Actively Recruiting

50

Hospital Clinic i Provincial de Barcelona

Barcelona, Spain

Actively Recruiting

51

Hospital Universitari Valle Hebrón de Barcelona

Barcelona, Spain

Actively Recruiting

52

Hospital Universitario Central de Asturias, Oviedo

Oviedo, Spain

Actively Recruiting

53

Luzerner Kantonsspital

Lucerne, Switzerland

Actively Recruiting

54

Civico, Ospedale Regionale

Lugano, Switzerland

Withdrawn

55

Royal Derby Hospital

Derby, United Kingdom

Not Yet Recruiting

56

Hull Royal Infirmary

Hull, United Kingdom

Actively Recruiting

57

Manchester Royal Infirmary

Manchester, United Kingdom

Actively Recruiting

58

Oxford University Hospital

Oxford, United Kingdom

Actively Recruiting

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Research Team

M

Michelle Durnan

S

Sammy Jassal

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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