Actively Recruiting

Phase 2
Age: 0 - 65Years
All Genders
NCT02918188

Therapeutic Effects of Hydrogen on Steroid-refractory/or Steroid-dependent cGVHD

Led by Navy General Hospital, Beijing · Updated on 2020-07-21

21

Participants Needed

1

Research Sites

782 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study suggested that hydrogen has a potential as an effective and safe therapeutic agent on cGVHD.

CONDITIONS

Official Title

Therapeutic Effects of Hydrogen on Steroid-refractory/or Steroid-dependent cGVHD

Who Can Participate

Age: 0 - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Written informed consent
  • Male or non-pregnant female
  • Patients younger than 65 years old
  • Diagnosis of chronic graft-versus-host disease that is steroid-refractory or steroid-dependent
  • Patient intolerant to steroid therapy
Not Eligible

You will not qualify if you...

  • Patients with stable disease not well controlled by current treatment
  • Pregnancy
  • HIV positive
  • Severe liver or renal impairment (serum creatinine >2.5 mg/dl; serum bilirubin >2.5 mg/dl without hepatic cGVHD)
  • Uncontrolled malignancies including persistence or relapse of hematopoietic malignancy
  • Use of any other investigational agents within the last four weeks
  • Cardiac insufficiency greater than grade II (New York Heart Association classification)
  • Inability to comply with medical therapy or follow-up

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Navy General Hospital

Beijing, Beijing Municipality, China, 100048

Actively Recruiting

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Research Team

L

Liren Qian, M.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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