Actively Recruiting
Thumb Proprioception in Trapeziometacarpal Osteoarthritis
Led by Hacettepe University · Updated on 2026-03-03
100
Participants Needed
1
Research Sites
27 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study looks at people who have osteoarthritis at the base of the thumb. It examines how well the thumb can sense its position and movement. The study has three goals: 1. To compare these measurements between people with thumb base osteoarthritis and healthy people. 2. To find out whether this ability changes from milder to more advanced levels of osteoarthritis. 3. To explore whether this ability is related to factors such as basic personal characteristics, thumb/hand muscle strength and hand use, pain and touch sensation, and emotional factors like fear of movement, anxiety, and depression. This is an observational study. No treatment is given. Participants complete thumb measurements and several tests/questionnaires.
CONDITIONS
Official Title
Thumb Proprioception in Trapeziometacarpal Osteoarthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Voluntary participation
- Radiographic Eaton-Littler stage I-IV confirmed by an orthopedic specialist (TMC OA group)
- Symptom duration of 6 months or more (TMC OA group)
- Age between 25 and 75 years
- Pain intensity of 4 or higher on the Visual Analog Scale during daily activities (TMC OA group)
- Ability to actively perform at least 40 degrees palmar abduction of the thumb (TMC OA group)
- Adequate cognitive ability to understand and perform study procedures (for participants aged 65 and older: MoCA score of 21 or higher)
- No thumb pain (Control group)
- No clinical signs of TMC osteoarthritis (Control group)
- Negative provocation tests (Control group)
You will not qualify if you...
- Inability to abduct the thumb beyond 40 degrees due to severe pain or deformity (especially advanced stage III-IV) (TMC OA group)
- Acute trauma or prior surgery of the hand or wrist
- Conservative treatment for hand or thumb pain in the same limb within the previous 6 months
- Current use of anti-inflammatory medication
- Peripheral nerve disorders affecting proprioception (e.g., carpal tunnel syndrome, dorsal radial nerve irritation, cervical radiculopathy, double crush syndrome)
- Concomitant upper-extremity musculoskeletal disorders (e.g., trigger finger, De Quervain's disease)
- Generalized joint hypermobility (Beighton score 4 or higher)
- Neuromuscular, systemic peripheral neuropathic, autoimmune, rheumatic, or infectious diseases
- Active cancer
- Neurological conditions affecting pain perception
- Visual impairment
- Pregnancy
- Exclusion criteria for the control group are the same as those for the TMC OA group
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hacettepe University
Ankara, Ankara, Turkey (Türkiye), 06100
Actively Recruiting
Research Team
M
Merve Sümeyye Yılmaz, PT
CONTACT
Ç
Çiğdem Ayhan Kuru, PT, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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