Actively Recruiting

Phase Not Applicable
Age: 18Years - 99Years
All Genders
NCT07295990

Tongue-strengthening Exercises in People With ALS.

Led by Nova Southeastern University · Updated on 2026-05-11

20

Participants Needed

1

Research Sites

139 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is testing a tongue exercise program for people living with ALS to see if it can help support speech and swallowing. All participants will receive the treatment, and researchers will measure changes over time by comparing each person's results to their own earlier results. People who join the study will have two in-person visits and four weekly telehealth sessions with a speech-language pathologist. During these sessions, participants will practice tongue resistance exercises, complete speech and swallowing tasks, and answer surveys about their experience. They will also use a small device at home to measure tongue strength and swallowing. The exercise program involves pressing the tongue against a device several times a day, five days per week, for five weeks. Researchers want to learn if this program is safe, practical, and helpful for people with ALS.

CONDITIONS

Official Title

Tongue-strengthening Exercises in People With ALS.

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of possible, probable, or definite ALS (El-Escorial Revisited)
  • No prior lingual exercises
  • Impaired tongue strength compared to normal data
  • EAT-10 score less than 3
Not Eligible

You will not qualify if you...

  • History of stroke
  • History of head injury
  • History of head and neck cancer
  • Presence of tracheostomy
  • Other neurogenic disorders
  • Recent oral surgery other than routine dental surgery
  • Unable to generate tongue pressure on manometer
  • Participation in another clinical trial that may affect results
  • Not able to eat or drink by mouth (NPO)
  • Unable to speak (anarthric)

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Nova Southeastern University

Davie, Florida, United States, 33314

Actively Recruiting

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Research Team

R

Raquel Garcia, SLP.D.

CONTACT

L

Lauren Tabor Gray, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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