Actively Recruiting
Transcranial Doppler, Optic Nerve Envelope Diameter and Quantitative Pupillometry Measurements in Postoperative Resuscitation Neurosurgery
Led by Centre Hospitalier Universitaire de la Réunion · Updated on 2023-05-06
230
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the use of non-invasive neuromonitoring tools, including transcranial doppler, optic nerve envelope diameter measurement, and quantitative pupillometry, in patients undergoing controlled intracranial surgery. These tools are commonly used in acute brain injury to detect intracranial hypertension, but their value in managing postoperative neurosurgery patients has not been established. The study aims to help detect early neurological deterioration after surgery. Participants will be monitored using these three non-invasive neuromonitoring methods starting one hour before surgery and continuing through regular assessments until four days after surgery. This observational study collects data over this postoperative period to understand how these measurements evolve. During the study, participants will undergo neuromonitoring assessments before surgery and regularly after surgery up to day four. The study measures changes in neuromonitoring signals from the three methods to track neurological status. Researchers will also gather clinical information and monitor participants in the postoperative resuscitation setting to assess the tools' usefulness in early detection of neurological issues.
CONDITIONS
Brief Title
Transcranial Doppler, Optic Nerve Envelope Diameter and Quantitative Pupillometry Measurements
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled controlled intracranial surgery more than 48 hours in advance
- French-speaking patient
- No opposition from patient or relative if patient cannot consent
You will not qualify if you...
- Chronic subdural haematoma
- Isolated cerebral endovascular procedure
- Stereotactic biopsy
- Scheduled ventriculoperitoneal shunt or isolated ventriculocisternostomy
- Known pupillary abnormalities, glaucoma, cataract surgery, or any ocular surgery (specific for pupillometry)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 hour before surgery
Participants undergo non-invasive neuromonitoring evaluations using transcranial doppler, optic nerve envelope diameter, and quantitative pupillometry before surgery.
1 visit (in-person)
Duration - 4 days post-surgery
Participants are monitored with non-invasive neuromonitoring measurements at regular times after surgery until Day 4.
Multiple visits over 4 days (in-person)
Trial Site Locations
Total: 1 location
1
CHU de la Réunion
Saint-Pierre, Reunion, 97448
Actively Recruiting
Research Team
R
Romain ASMOLOV, MD
L
Laetitia BERLY, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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