Actively Recruiting
Treatment of Desmoid Fibromatosis With Arterial Embolization
Led by Istituto Ortopedico Rizzoli · Updated on 2025-09-12
20
Participants Needed
1
Research Sites
187 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Desmoid fibromatoses are rare and locally aggressive mesenchymal tumors. The current scientific evidence regarding the efficacy and safety of the treatment of desmoid fibromatosis by arterial embolization is constituted by several retrospective and prospective studies. These studies report promising results through the use of chemoembolization, that is, arterial embolization using particles loaded with chemotherapy. Instead, the type of treatment we propose would consist of injection of embolizing material without the use of chemotherapy, based on the positive results we have consistently reported over the years on arterial embolization of musculoskeletal tumors.
CONDITIONS
Official Title
Treatment of Desmoid Fibromatosis With Arterial Embolization
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients of both sexes aged 12 years
- Symptomatic and active desmoid fibromatosis with documented growth at recent follow-ups
- Patients not eligible for surgery or cryoablation
- Patients who have had embolization surgery for desmoid fibromatosis from 01/01/2023 onward and new patients scheduled for this treatment
- Signed informed consent to participate in the study
You will not qualify if you...
- Patients with life expectancy less than 3 months or severely impaired functional status (ASA 4)
- Patients with desmoid fibromatosis not in active phase, confirmed clinically and by imaging (MRI, CT)
- Patients with coagulation deficiencies or plateletopenic diseases
- Patients with documented active infections
- Patients unable to undergo MRI examination
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Istituto Ortopedico Rizzoli
Bologna, BO, Italy, 40136
Actively Recruiting
Research Team
G
Giancarlo Facchini, Medicine and Surgery
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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