Comparing Combined Cataract and Vitrectomy Surgery Versus Vitrectomy Alone for Retinal Detachment Repair in Adults 50 and Older

What this Trial Is About

Rhegmatogenous retinal detachment RRD is a condition where the retina detaches from the back wall of the eye, causing vision loss that requires surgery. This trial evaluates two surgical approaches for adults aged 50 and older with non-highly myopic RRD who have not had previous vitreoretinal surgery. It compares vitrectomy alone, the standard care, with combined vitrectomy and cataract surgery phacovitrectomy to determine which offers better outcomes, safety, and patient experience. Participants are randomly assigned to one of two groups. One group undergoes vitrectomy to repair the retina and may have cataract surgery later if needed. The other group receives both vitrectomy and cataract removal with intraocular lens implantation during the same surgery. The surgeries follow standard care procedures, including vitrectomy with various gauge sizes and tamponade agent choice at the surgeons discretion. A special protocol guides lens selection when the macula is detached during combined surgery. During the 52 weeks after surgery, participants are monitored for vision quality using best-corrected visual acuity, success of retinal reattachment, complications, additional surgeries, quality of life, patient satisfaction, and healthcare costs. Assessments include visual tests, patient questionnaires, and safety monitoring. Interviews are also conducted to understand patient experiences and acceptability of each surgical approach. The trial aims to provide evidence on clinical and cost-effectiveness to guide treatment decisions for RRD.

Treatment of Retinal Detachment in People Who Have Not Had Cataract Surgery With Vitrectomy vs Vitrectomy and Cataract Removal