Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06610877

Ultrasound Neuromodulation in Essential Tremor

Led by University of California, San Francisco · Updated on 2026-03-06

60

Participants Needed

1

Research Sites

125 weeks

Total Duration

On this page

Sponsors

U

University of California, San Francisco

Lead Sponsor

F

Focused Ultrasound Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is being done to test whether low-intensity focused ultrasound (LIFU) (low energy sound waves) cause temporary changes in brain activity and behavior when directed at particular parts of the brain. By targeting LIFU to the parts of the brain thought to be responsible for essential tremor (ET), and measuring any associated improvement in tremor, the investigators hope to show that LIFU can be a useful tool for studying the brain circuits responsible for tremor and other brain disorders.

CONDITIONS

Official Title

Ultrasound Neuromodulation in Essential Tremor

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with medically refractory tremor scheduled to undergo MR-guided high-intensity focused ultrasound (HIFU) thalamotomy to treat their tremor at UCSF.
Not Eligible

You will not qualify if you...

  • Patients with MR-conditional pacemakers are excluded due to MRI and monitoring complexity.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Pritzker Building, UCSF

San Francisco, California, United States, 94107

Actively Recruiting

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Research Team

L

Leo P. Sugrue, MD, PhD

CONTACT

T

Tommaso Di Ianni, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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Ultrasound Neuromodulation in Essential Tremor | DecenTrialz