Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
All Genders
Healthy Volunteers
NCT07026175

Unravelling Energy Issues Underpinning Low Energy Availability in High Performance Athletes

Led by Australian Catholic University · Updated on 2025-06-18

20

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

Sponsors

A

Australian Catholic University

Lead Sponsor

W

Wu Tsai Human Performance Alliance

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to understand how the body responds to short-term, severe low energy availability (LEA) in healthy, weight-bearing endurance athletes aged 18-45 years old. LEA describes a mismatch between an individual's dietary energy intake and the energy cost of their commitments for training and competition. The main questions this trial aims to answer are: 1. What effect does short-term, severe LEA have on sleeping metabolic rate? 2. What effect does short-term, severe LEA have on other body systems identified within the Relative Energy Deficiency in Sport (REDs) Health and Performance Conceptual models? Researchers will compare a control trial with both a LEA trial achieved through diet restriction and a LEA trial achieved through increased exercise to see if there are differences in the body's response. Participants will complete three 6-day trials, a minimum of 3-weeks apart, involving: * Prescribed diet (all food provided) * Prescribed running and/or cycling exercise * Two visits to ACU Fitzroy campus for blood tests and exercise testing * 50 hour stay (two nights and two days) in the ACU metabolic chamber

CONDITIONS

Official Title

Unravelling Energy Issues Underpinning Low Energy Availability in High Performance Athletes

Who Can Participate

Age: 18Years - 45Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18 to 45 years
  • Well-trained weight-bearing athlete (tier 2-4)
  • Perform approximately 45 km per week of weight-bearing endurance training
  • Able to undertake prescribed exercise in each trial condition
  • Pass the ESSA pre-exercise screening tool or have GP clearance to exercise
Not Eligible

You will not qualify if you...

  • Assessment of red status on the Relative Energy Deficiency in Sport Clinical Assessment Tool
  • Unable to attend 6 study visits at ACU Fitzroy, Victoria
  • Pregnancy
  • Use of hormonal contraceptives within the last 3 months
  • Onset of peri/menopause

AI-Screening

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Trial Site Locations

Total: 1 location

1

Australian Catholic University

Fitzroy, Victoria, Australia, 3065

Actively Recruiting

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Research Team

L

Louise M Burke, PhD

CONTACT

M

Margot A Rogers, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

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