Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT04524637

The Utility of Thromboelastography in Traumatic Brain Injury

Led by Shanghai 6th People's Hospital · Updated on 2025-03-17

500

Participants Needed

1

Research Sites

486 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Hemocoagulation disorder is recognized to have crucial effects on hemorrhagic or ischemic diseases. Coagulation-related damages secondary to traumatic brain injury are common and severe secondary insults of head trauma and often leads to a poor prognosis. In this study, we sought to assess if posttraumatic hemocoagulation disorders determined using thromboelastography are associated with coagulation-related damages secondary to traumatic brain injury, and evaluate their influence on outcome among patients with head trauma. Based on above results, prediction models or risk scoring systems will be further developed and validated to predict coagulation-related damages secondary to traumatic brain injury.

CONDITIONS

Official Title

The Utility of Thromboelastography in Traumatic Brain Injury

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients who arrive at the hospital within 24 hours after head trauma
  • Patients with isolated traumatic brain injury having an abbreviated injury score (AIS) of 3 or less for other body regions
Not Eligible

You will not qualify if you...

  • Patients with existing prior neurological disease
  • Patients with known coagulation disorders
  • Patients on anticoagulants or medications affecting coagulation within 30 days before trauma
  • Patients receiving blood components before blood draw
  • Patients who deteriorate and die before coagulation-related damage can be assessed

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Shanghai Sixth People's Hospital

Shanghai, China, 200233

Actively Recruiting

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Research Team

H

Hao Chen, M.D., Ph.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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The Utility of Thromboelastography in Traumatic Brain Injury | DecenTrialz