Actively Recruiting
Validating Speckle Tracking Methods on Soft Tissue Strain, Displacement, and Roles in Physical Therapy: Ligaments, Tendons, and Muscles with Exercise Intervention
Led by National Taiwan University Hospital · Updated on 2026-03-20
80
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying how the strain and movement of human soft tissues like ligaments, tendons, and muscles are affected by physical activity, injury, and training over three years. The project focuses on three areas: the ulnar collateral ligament (UCL) in baseball pitchers, the tibialis posterior tendon in people with dysfunction, and the hamstring muscles after anterior cruciate ligament (ACL) reconstruction. Ultrasound techniques will be used to analyze tissue behavior and help improve injury risk assessment, treatment, and rehabilitation. The study includes three phases. In the first year, male collegiate baseball pitchers with different injury risks will have their elbow ligaments examined, followed by an 8-week blood flow restriction training program for some participants. The second year will examine tendon strain and rotation in people with posterior tibial tendon dysfunction compared to healthy controls. The third year involves patients after ACL reconstruction undergoing 8 weeks of Nordic hamstring exercise training to assess muscle strain and activity. Participants will undergo ultrasound and elastography assessments to measure strain, displacement, rotation, and muscle strength at various time points, including before and after training programs. Researchers will track changes during the treatments and compare results across groups to understand tissue adaptations related to injury and training. The total study duration is three years with detailed monitoring and evaluations throughout each phase.
CONDITIONS
Brief Title
Validating the Speckle Tracking Methods on Soft Tissue Strain, Displacement, and Roles in Physical Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male pitchers aged between 18 and 35 years
- More than five years of pitching experience
- At least 200 counts of pitching training per week
- Age between 20 and 65 years
- Diagnosed with grade II posterior tibial tendon dysfunction and recommended for surgery
- Age between 18 and 45 years
- Underwent unilateral anterior cruciate ligament semitendinosus tendon reconstruction within past 6 years
- Able to fully participate in pre-injury sports and training
You will not qualify if you...
- Diagnosed with partial or full thickness UCL tears by MR imaging
- Positive moving valgus stress test
- Unable to participate in regular baseball pitching training or absent from competition between March 2023 and March 2025
- Signs suggesting UCL injury on ultrasound
- Compliance rate below 80% in eight-week blood flow restriction training
- Lower extremities with prior surgical intervention
- History of nerve or vascular injury in lower extremities
- Known ligament tears in ankles and feet
- Fixed foot joint deformities
- Known physical conditions affecting the experiment
- Orthopedic conditions preventing competition participation such as arthritis or knee pain
- Hamstring muscle strain in knee within past 3 months
- Attendance rate below 80% in eight-week training after ACL reconstruction
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 8 weeks
Participants receive 8 weeks of specific exercise training based on their group assignment, including blood flow restriction training or Nordic exercise training.
Weekly visits for up to 8 weeks
Trial Site Locations
Total: 1 location
1
School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University
Taipei, Taiwan, 100025
Actively Recruiting
Research Team
M
Ming-Wei Wang, PhD candidate
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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