Actively Recruiting
Vertebral Artery Origin Treatment Via Endovascular Techniques Registry (VOTER)
Led by St. Louis University · Updated on 2025-02-12
150
Participants Needed
10
Research Sites
39 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research investigates patients who have experienced a stroke and have evidence of narrowing in the vertebral artery origin, a condition known as Vertebral Artery Origin Stenosis (VAOS). The study collects information from both past and current patients to better understand clinical outcomes following treatment for this condition. It focuses on patients who have had a posterior circulation ischemic event and confirmed artery disease, aiming to evaluate the results of different management approaches over time. The study includes a registry that tracks patients who underwent stenting along with medical management to prevent another stroke. It gathers data on clinical outcomes up to 18 months after treatment. Originally designed as a prospective registry, the study changed to a retrospective format in January 2025, meaning it now collects and analyzes information from past cases rather than following patients forward in time. Participants' health data, including clinical and angiographic outcomes, are collected at 30 days and one year after treatment. Researchers measure the incidence of recurrent stroke or death within one year post-treatment and also track the occurrence of artery narrowing returning (restenosis). The study lasts up to 18 months post-treatment, during which participants' progress and outcomes are monitored to understand the effectiveness and safety of the treatments used.
CONDITIONS
Brief Title
Vertebral Artery Origin Treatment Via Endovascular Techniques Registry (VOTER)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients between 18 and 90 years of age
- Patient has experienced a posterior circulation ischemic event
- Patient has angiographically confirmed bilateral vertebral artery origin disease (hypoplasia, occlusion, or stenosis)
- Patient has more than 50% stenosis on the side being targeted for therapy
You will not qualify if you...
- Pregnant women
- Contrast indication to the use of anti-platelet drugs
- There is tandem vertebral or basilar artery stenosis
- Serum creatinine is greater than 2.5
- Baseline modified Rankin score is greater than 3
- Life expectancy less than 5 years
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 18 months post-treatment
Participants who have undergone stenting plus medical management for vertebral artery origin stenosis are observed to collect information on clinical and angiographic outcomes.
Visits at 30 days and 1 year post-treatment
Trial Site Locations
Total: 10 locations
1
Baptist Medical Center Jacksonville
Jacksonville, Florida, United States, 32207
Actively Recruiting
2
University of Southern Florida
Tampa, Florida, United States, 33606
Actively Recruiting
3
Northwestern Medicine Regional Medical Group
Winfield, Illinois, United States, 60190
Actively Recruiting
4
University of Iowa
Iowa City, Iowa, United States, 52242
Actively Recruiting
5
SSM DePaul Hospital
Bridgeton, Missouri, United States, 63044
Actively Recruiting
6
Saint Louis University
St Louis, Missouri, United States, 63110
Actively Recruiting
7
Cleveland Clinic
Cleveland, Ohio, United States, 44195
Not Yet Recruiting
8
Mercy Health Neuroscience Institute
Toledo, Ohio, United States, 43608
Actively Recruiting
9
Semmes Murphey Clinic
Memphis, Tennessee, United States, 38120
Actively Recruiting
10
Texas Tech University Health Science Center of El Paso
El Paso, Texas, United States, 79905
Not Yet Recruiting
Research Team
R
Randall Edgell, MD
M
Mollie Hoffmeyer, RN, BSN
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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