Lose Little, Live Longer: A Randomised Controlled Feasibility Trial of a Diet and Exercise Weight Management Intervention for Overweight Chinese Cancer Survivors

What this Trial Is About

This research aims to assess the feasibility and acceptability of a randomized controlled trial evaluating an adaptive weight management intervention for Chinese cancer survivors who are overweight or obese after completing their cancer survivorship care. The study focuses on improving body weight, BMI, dietary quality, physical activity, physical and psychosocial functioning, self-efficacy for weight loss, and quality of life. It follows guidelines for feasibility trials without setting hypotheses, as the main goal is to prepare for a larger trial. The trial has three study groups: the experimental group receives the Lose Little, Live Longer (L4) weight management intervention, a therapist-led program delivered in group phone sessions over five weeks focusing on diet, exercise, self-efficacy, and craving management. The active control group receives five weekly educational videos promoting balanced diet and physical activity through instant messaging. The waitlist control group receives pamphlets with general diet and activity information and will be offered the L4 intervention after the study. Participants will be assessed at baseline, immediately post-intervention, and at 3 and 6 months post-intervention for outcomes including recruitment and retention rates, adherence, weight and BMI changes, self-efficacy, dietary assessment, skin carotenoid status, physical activity, and quality of life measures. The study includes questionnaires, physical and psychosocial evaluations, and tracking of missing data. The total participation duration covers intervention delivery and follow-up assessments extending to six months post-intervention.

A Weight Management Intervention for Overweight Chinese Cancer Survivors