Actively Recruiting
Xiangya Cardiopulmonary Health and Disease Cohort Observational Study Using Retrospective and Prospective Data to Evaluate Heart and Lung Function
Led by Xiangya Hospital of Central South University · Updated on 2025-07-02
30000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are conducting the Xiangya Cardiopulmonary Health and Disease Cohort, an observational study designed to systematically evaluate cardiopulmonary function in various health states. This study combines retrospective and prospective data to understand the relationship between heart and lung function across resting, exercise, and sleep scenarios. It aims to identify key indicators of cardiopulmonary health, develop a risk stratification system, and explore how comorbid heart and lung conditions affect long-term outcomes. The study integrates historical hospital records including cardiac and pulmonary function tests, clinical diagnoses, treatments, and imaging reports. Patients treated at Xiangya Hospital from 2010 to 2025 who meet criteria are included in the retrospective cohort. Those who consent will enter a prospective cohort with at least 3 years of follow-up and dynamic monitoring of cardiopulmonary function. The study will use data mining and clustering methods to classify patients by risk and analyze disease progression and comorbidity patterns. Participants provide cardiopulmonary assessments, questionnaires, and clinical data at baseline and during follow-up. The study will monitor death events for up to 10 years and measure secondary outcomes such as quality of life, hospitalization costs, and incidence of cardiometabolic and respiratory diseases over an average of 3 years. This comprehensive approach aims to improve diagnosis, prognosis, and treatment planning for cardiopulmonary diseases through better understanding of heart-lung interactions.
CONDITIONS
Brief Title
Xiangya Cardiopulmonary Health and Disease Cohort
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients treated or hospitalized at Xiangya Hospital from January 2010 to April 2025
- Completed cardiac (e.g., echocardiography) and pulmonary function tests within one year of each other
- Have complete clinical diagnostic and treatment information excluding cardiopulmonary function test report
- For prospective cohort: patients from retrospective cohort who consent to at least 3 years of follow-up
- Able to complete baseline assessments and stable for follow-up with valid contact information
You will not qualify if you...
- Missing cardiopulmonary function test reports or key data such as VO2peak, FEV1/FVC, LVEF
- Missing key clinical diagnostic or treatment data
- Severe cognitive impairment, psychiatric disease, or communication disorders preventing follow-up
- Expected survival less than 3 years due to advanced illness
- Incomplete cardiopulmonary or clinical data at baseline
- Participation in other interventional clinical trials that may interfere with cardiopulmonary assessments
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Retrospective data collected from January 2010 to April 2025
Participants undergo cardiopulmonary function tests and clinical assessments to establish baseline health status.
Data collected from past medical records
Duration - At least 3 years
Participants in the prospective cohort are followed for at least 3 years with ongoing monitoring of cardiopulmonary function and health outcomes.
Periodic follow-up visits during the monitoring period
Trial Site Locations
Total: 1 location
1
Xiangya Hospital, Central South University Affiliated
Changsha, Hunan, China, 457500
Actively Recruiting
Research Team
Y
yuan zhang, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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