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All Genders
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ID06972784

Xiangya Cardiopulmonary Health and Disease Cohort Observational Study Using Retrospective and Prospective Data to Evaluate Heart and Lung Function

Led by Xiangya Hospital of Central South University · Updated on 2025-07-02

30000

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are conducting the Xiangya Cardiopulmonary Health and Disease Cohort, an observational study designed to systematically evaluate cardiopulmonary function in various health states. This study combines retrospective and prospective data to understand the relationship between heart and lung function across resting, exercise, and sleep scenarios. It aims to identify key indicators of cardiopulmonary health, develop a risk stratification system, and explore how comorbid heart and lung conditions affect long-term outcomes. The study integrates historical hospital records including cardiac and pulmonary function tests, clinical diagnoses, treatments, and imaging reports. Patients treated at Xiangya Hospital from 2010 to 2025 who meet criteria are included in the retrospective cohort. Those who consent will enter a prospective cohort with at least 3 years of follow-up and dynamic monitoring of cardiopulmonary function. The study will use data mining and clustering methods to classify patients by risk and analyze disease progression and comorbidity patterns. Participants provide cardiopulmonary assessments, questionnaires, and clinical data at baseline and during follow-up. The study will monitor death events for up to 10 years and measure secondary outcomes such as quality of life, hospitalization costs, and incidence of cardiometabolic and respiratory diseases over an average of 3 years. This comprehensive approach aims to improve diagnosis, prognosis, and treatment planning for cardiopulmonary diseases through better understanding of heart-lung interactions.

CONDITIONS

Brief Title

Xiangya Cardiopulmonary Health and Disease Cohort

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients treated or hospitalized at Xiangya Hospital from January 2010 to April 2025
  • Completed cardiac (e.g., echocardiography) and pulmonary function tests within one year of each other
  • Have complete clinical diagnostic and treatment information excluding cardiopulmonary function test report
  • For prospective cohort: patients from retrospective cohort who consent to at least 3 years of follow-up
  • Able to complete baseline assessments and stable for follow-up with valid contact information
Not Eligible

You will not qualify if you...

  • Missing cardiopulmonary function test reports or key data such as VO2peak, FEV1/FVC, LVEF
  • Missing key clinical diagnostic or treatment data
  • Severe cognitive impairment, psychiatric disease, or communication disorders preventing follow-up
  • Expected survival less than 3 years due to advanced illness
  • Incomplete cardiopulmonary or clinical data at baseline
  • Participation in other interventional clinical trials that may interfere with cardiopulmonary assessments

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Retrospective data collected from January 2010 to April 2025

Participants undergo cardiopulmonary function tests and clinical assessments to establish baseline health status.

Data collected from past medical records

Long-term Monitoring

Duration - At least 3 years

Participants in the prospective cohort are followed for at least 3 years with ongoing monitoring of cardiopulmonary function and health outcomes.

Periodic follow-up visits during the monitoring period

Trial Site Locations

Total: 1 location

1

Xiangya Hospital, Central South University Affiliated

Changsha, Hunan, China, 457500

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Research Team

Y

yuan zhang, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Frequently Asked Questions

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