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Phase Not Applicable
Age: 18Years +
All Genders
ID06383585

Evaluation of 3D DL oZTEo in the Detection of Osseous Changes in Patients With Inflammatory Arthritis

Led by Mayo Clinic · Updated on 2025-12-17

25

Participants Needed

1

Research Sites

26 weeks

Total Duration

On this page

Sponsors

M

Mayo Clinic

Lead Sponsor

G

GE Healthcare

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating a new MRI pulse sequence called 3D DL oZTEo to detect bone erosions in the hands of patients with inflammatory arthritis. The study aims to validate this technique against current standard methods like radiography and conventional MRI, as these structural changes are important for diagnosis and treatment decisions in rheumatic conditions. This is an interventional study conducted at Mayo Clinic. Participants will have the FDA-approved oZTEo MRI pulse sequence added to their routine hand MRI scan. The oZTEo images will be anonymized and processed using a deep learning algorithm developed by GE Healthcare. This additional sequence is assessed alongside the standard MRI to compare its ability to detect bone erosions. During the study, researchers will analyze MRI scans with and without the 3D DL oZTEo sequence to determine the presence and number of bone erosions in the hand. Participants must have recent hand radiographs confirming erosions and are scheduled for hand MRI as part of their clinical care. The study measures outcomes on the day of imaging and monitors the accuracy of erosion detection.

CONDITIONS

Brief Title

3D DL Ozteo in the Detection of Osseous Changes in Patients With Inflammatory Arthritis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients 18 years of age
  • Hand radiographs performed within the past 3-6 months with imaging results available for analysis
  • Hand radiographs confirm the presence of bony erosions
  • Scheduled for a hand MRI as part of their routine clinical care at Mayo Clinic Rochester
Not Eligible

You will not qualify if you...

  • Less than 18 years of age

Research Team

N

Naveen S Murthy, MD

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