Actively Recruiting
7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)
Led by University of Missouri-Columbia · Updated on 2025-12-02
20
Participants Needed
1
Research Sites
95 weeks
Total Duration
On this page
Sponsors
U
University of Missouri-Columbia
Lead Sponsor
S
Siemens Medical Solutions
Collaborating Sponsor
AI-Summary
What this Trial Is About
Comparison of a 7t MRI to standard of care 1.5t/3t MRI scans to determine if earlier detection of brain metastases are possible on a 7t.
CONDITIONS
Official Title
7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically confirmed diagnosis of small-cell lung cancer (SCLC)
- Brain MRI (1.5T or 3T) performed within 4 weeks prior to consent showing no brain metastases or leptomeningeal disease
- No history of brain metastases or leptomeningeal disease
- Refusal of prophylactic cranial irradiation (PCI) and agreement to surveillance with brain MRI scans (1.5T/3T)
- Age 18 years or older
- ECOG Performance Status of 0 to 2
- Ability to tolerate the 7T MRI scan
You will not qualify if you...
- Contraindications to MRI such as implanted metal devices or foreign bodies
- Contraindications to gadolinium contrast administration during MRI
- Presence of other metastatic malignancies requiring active treatment
- Pregnancy (pregnancy status will be confirmed verbally)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Missouri
Columbia, Missouri, United States, 65212
Actively Recruiting
Research Team
B
Brooke McDaniel
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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