Status:

COMPLETED

Drug Treatment for Alcoholics With Post-Traumatic Stress Disorder

Lead Sponsor:

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Conditions:

Alcoholism

Post-Traumatic Stress Disorder

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

This study will investigate the use of sertraline (Zoloft) to decrease alcohol consumption and crime-related post-traumatic stress disorder in those individuals with both disorders. This will be a 12-...

Eligibility Criteria

Inclusion Criteria:

  • Meets criteria for alcohol abuse or dependence and post-traumatic stress disorder.
  • Laboratory tests for blood and urinalysis must be within normal limits.
  • Must be clearly motivated to obtain benefit from treatment and keep appointments for study visits and therapy sessions.
  • Females who use an acceptable method of birth control, are sterilized, or are at least 2 years post-menopausal.

Exclusion Criteria:

  • Have a diagnosis of schizophrenia, bipolar affective disorder, dissociative identity disorder, eating disorder, substance dependence in the last 60 days.
  • Currently suicidal.
  • Medical reasons not to receive drug therapy.
  • Allergy or hypersensitivity to selective serotonin inhibitor antidepressants.
  • Significant hematological, endocrine, cardiovascular, renal, hepatic, neurological, or gastrointestinal disease.
  • Liver function test greater than 2 times the normal level
  • Require ongoing therapy with another psychoactive drug during the study period.
  • Females who are pregnant or lactating.

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

End Date :

December 1 2000

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00000446

End Date

December 1 2000

Last Update

June 24 2005

Active Locations (1)

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1

Department of Psychiatry and Behavioral Science, Medical University of South Carolina

Charleston, South Carolina, United States, 29425