Completed
Sertraline Treatment in Comorbid Post-Traumatic Stress Disorder and Alcoholism
Led by National Institute on Alcohol Abuse and Alcoholism (NIAAA) · Updated on 2005-06-24
N/A
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will investigate the use of sertraline (Zoloft) to decrease alcohol consumption and crime-related post-traumatic stress disorder in those individuals with both disorders. This will be a 12-week, placebo-controlled, double-blind outpatient trial. All subjects will receive cognitive behavioral therapy in addition to a placebo or sertraline. Comprehensive evaluation will be done at study entry; treatment termination; and 6, 9, and 12 months after study entry.
CONDITIONS
Official Title
Drug Treatment for Alcoholics With Post-Traumatic Stress Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Meets criteria for alcohol abuse or dependence and post-traumatic stress disorder.
- Laboratory tests for blood and urinalysis must be within normal limits.
- Must be clearly motivated to obtain benefit from treatment and keep appointments for study visits and therapy sessions.
- Females who use an acceptable method of birth control, are sterilized, or are at least 2 years post-menopausal.
You will not qualify if you...
- Have a diagnosis of schizophrenia, bipolar affective disorder, dissociative identity disorder, eating disorder, substance dependence in the last 60 days.
- Currently suicidal.
- Medical reasons not to receive drug therapy.
- Allergy or hypersensitivity to selective serotonin inhibitor antidepressants.
- Significant hematological, endocrine, cardiovascular, renal, hepatic, neurological, or gastrointestinal disease.
- Liver function test greater than 2 times the normal level
- Require ongoing therapy with another psychoactive drug during the study period.
- Females who are pregnant or lactating.
Trial Site Locations
Total: 1 location
1
Department of Psychiatry and Behavioral Science, Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Status Unknown
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
N/A
Primary Purpose
TREATMENT
Number of Arms
0
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