Status:
COMPLETED
Drug Treatment for Alcoholics With Post-Traumatic Stress Disorder
Lead Sponsor:
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Conditions:
Alcoholism
Post-Traumatic Stress Disorder
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
This study will investigate the use of sertraline (Zoloft) to decrease alcohol consumption and crime-related post-traumatic stress disorder in those individuals with both disorders. This will be a 12-...
Eligibility Criteria
Inclusion Criteria:
- Meets criteria for alcohol abuse or dependence and post-traumatic stress disorder.
- Laboratory tests for blood and urinalysis must be within normal limits.
- Must be clearly motivated to obtain benefit from treatment and keep appointments for study visits and therapy sessions.
- Females who use an acceptable method of birth control, are sterilized, or are at least 2 years post-menopausal.
Exclusion Criteria:
- Have a diagnosis of schizophrenia, bipolar affective disorder, dissociative identity disorder, eating disorder, substance dependence in the last 60 days.
- Currently suicidal.
- Medical reasons not to receive drug therapy.
- Allergy or hypersensitivity to selective serotonin inhibitor antidepressants.
- Significant hematological, endocrine, cardiovascular, renal, hepatic, neurological, or gastrointestinal disease.
- Liver function test greater than 2 times the normal level
- Require ongoing therapy with another psychoactive drug during the study period.
- Females who are pregnant or lactating.
Key Trial Info
Start Date :
Trial Type :
INTERVENTIONAL
End Date :
December 1 2000
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00000446
End Date
December 1 2000
Last Update
June 24 2005
Active Locations (1)
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1
Department of Psychiatry and Behavioral Science, Medical University of South Carolina
Charleston, South Carolina, United States, 29425