Actively Recruiting
AB Gait Estim Neurophysiology
Led by Emory University · Updated on 2025-07-28
50
Participants Needed
1
Research Sites
146 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is being done to answer the question: What are the effects of electrical stimulation and stepping practice on connections between the brain and muscles? The long-term goal of this project is to develop novel, effective, and personalized rehabilitation protocols founded on an understanding of neurobiological mechanisms that combine electrical stimulation with gait training to improve gait performance in older adults and stroke survivors. The rationale of this project is to explore and generate preliminary data regarding how electrical stimulation-based strategies modulate cortical and spinal circuits in able-bodied individuals. The researchers will evaluate the effects of short treadmill walking bouts or single gait training sessions with and without electrical stimulation on somatosensory, spinal-reflex, corticospinal circuit neurophysiology, and/or gait performance. The study will provide important preliminary and normative data that can explain how brain circuits change with stimulation or stepping practice and inform future rehabilitation studies on patients. The study population is able-bodied individuals.
CONDITIONS
Official Title
AB Gait Estim Neurophysiology
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 65 years
- Able-bodied without physical disability, neurological, orthopedic, or other medical disorders affecting walking or study participation
- Ability to walk more than 10 meters overground and for 1 minute on a treadmill
- Ability to follow 3-stage commands and provide informed consent
You will not qualify if you...
- History or evidence of orthopedic or physical disability
- History or evidence of neurological pathology
- Pregnancy (female)
- Uncontrolled hypertension
- Having a cardiac pacemaker or other implanted electronic system
- Skin conditions preventing electrical stimulation setup
- Impaired sensation in the left upper limb
- Bruises or cuts at the stimulation electrode placement site
- Currently enrolled in rehabilitation or another investigational study
- Severe uncontrolled medical problems such as hypertension, cardiovascular disease, rheumatoid arthritis, active cancer, renal disease, or epilepsy
- Contraindications to transcranial magnetic stimulation such as metal implants, medications increasing cortical excitability, or unexplained dizziness in past 6 months
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Emory University
Atlanta, Georgia, United States, 30329
Actively Recruiting
Research Team
T
Trisha Kesar, PT, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
FACTORIAL
Primary Purpose
OTHER
Number of Arms
3
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