Actively Recruiting

All Genders
ID06920303

Accuracy of Transcranial Colour Coded Duplex Compared With CT Angiography in Diagnosing Arterial Obstructions in Acute Ischemic Strokes

Led by Sohag University · Updated on 2025-05-13

100

Participants Needed

1

Research Sites

34 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Cerebrovascular stroke is a leading cause of death and disability worldwide, with atherosclerosis being a major cause of ischemic strokes through vessel narrowing and blockages. Intracranial stenosis often results in recurrent ischemic strokes or transient ischemic attacks, and its severity can influence the extent of brain injury. The prevalence of intracranial arterial stenosis varies among ethnic groups and is notably common in the Egyptian stroke population. Researchers are evaluating the accuracy of transcranial colour coded duplex, a non-invasive ultrasound tool that measures blood flow velocity and detects blockages in intracranial arteries, compared with CT angiography in patients with acute ischemic strokes or transient ischemic attacks. The study includes patients admitted to the neurology and stroke unit at Sohag University Hospital. Participants will undergo transcranial colour coded duplex and CT angiography to detect arterial obstructions. The study aims to assess the accuracy of the duplex method one year after enrolling 100 patients. Researchers will monitor cerebral blood flow and arterial blockage detection, with no invasive procedures beyond routine imaging. The total participation duration varies but includes comprehensive diagnostic assessments to compare these imaging techniques.

CONDITIONS

Brief Title

Accuracy of Transcranial Colour Coded Duplex in Comparing With CT Angiography

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients who have acute ischemic strokes or transient ischemic attacks
Not Eligible

You will not qualify if you...

  • History of cardiac arrhythmia or known rheumatic heart disease
  • History of autoimmune diseases
  • Presence of space occupying lesion or hemorrhage in CT brain
  • Pregnant female
  • Refusal to participate in the study
  • History of allergy or acute kidney injury from previous dye injection
  • Chronic kidney disease
  • Premorbid neurological disorders such as myopathy or multiple sclerosis
  • Inability to achieve safe vascular access
  • Insufficient temporal acoustic window for imaging

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to 1 year

Participants undergo transcranial colour coded duplex and CT angiography to diagnose arterial obstructions related to acute ischemic stroke.

1 to 2 visits depending on imaging needs

Long-term Monitoring

Duration - Up to 1 year after enrollment

Participants are monitored for outcomes related to arterial obstructions and stroke progression after initial diagnostic procedures.

Follow-up visits as needed over 1 year

Trial Site Locations

Total: 1 location

1

Sohag university hospital

Sohag, Egypt

Actively Recruiting

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Research Team

H

Hassan H Accuracy of Transcranial Colour Coded duplex Compared With CT, resident

H

Hazem K Ebrahim, professor

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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