Actively Recruiting
Accuracy of Transcranial Colour Coded Duplex Compared With CT Angiography in Diagnosing Arterial Obstructions in Acute Ischemic Strokes
Led by Sohag University · Updated on 2025-05-13
100
Participants Needed
1
Research Sites
34 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Cerebrovascular stroke is a leading cause of death and disability worldwide, with atherosclerosis being a major cause of ischemic strokes through vessel narrowing and blockages. Intracranial stenosis often results in recurrent ischemic strokes or transient ischemic attacks, and its severity can influence the extent of brain injury. The prevalence of intracranial arterial stenosis varies among ethnic groups and is notably common in the Egyptian stroke population. Researchers are evaluating the accuracy of transcranial colour coded duplex, a non-invasive ultrasound tool that measures blood flow velocity and detects blockages in intracranial arteries, compared with CT angiography in patients with acute ischemic strokes or transient ischemic attacks. The study includes patients admitted to the neurology and stroke unit at Sohag University Hospital. Participants will undergo transcranial colour coded duplex and CT angiography to detect arterial obstructions. The study aims to assess the accuracy of the duplex method one year after enrolling 100 patients. Researchers will monitor cerebral blood flow and arterial blockage detection, with no invasive procedures beyond routine imaging. The total participation duration varies but includes comprehensive diagnostic assessments to compare these imaging techniques.
CONDITIONS
Brief Title
Accuracy of Transcranial Colour Coded Duplex in Comparing With CT Angiography
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who have acute ischemic strokes or transient ischemic attacks
You will not qualify if you...
- History of cardiac arrhythmia or known rheumatic heart disease
- History of autoimmune diseases
- Presence of space occupying lesion or hemorrhage in CT brain
- Pregnant female
- Refusal to participate in the study
- History of allergy or acute kidney injury from previous dye injection
- Chronic kidney disease
- Premorbid neurological disorders such as myopathy or multiple sclerosis
- Inability to achieve safe vascular access
- Insufficient temporal acoustic window for imaging
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 1 year
Participants undergo transcranial colour coded duplex and CT angiography to diagnose arterial obstructions related to acute ischemic stroke.
1 to 2 visits depending on imaging needs
Duration - Up to 1 year after enrollment
Participants are monitored for outcomes related to arterial obstructions and stroke progression after initial diagnostic procedures.
Follow-up visits as needed over 1 year
Trial Site Locations
Total: 1 location
1
Sohag university hospital
Sohag, Egypt
Actively Recruiting
Research Team
H
Hassan H Accuracy of Transcranial Colour Coded duplex Compared With CT, resident
H
Hazem K Ebrahim, professor
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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