Actively Recruiting

Phase Not Applicable
Age: 1Day - 89Years
All Genders
NCT06545760

Admission to Kangaroo Mother Care (KMC) Ward and Maternal Postpartum Depression

Led by University of Alabama at Birmingham · Updated on 2026-04-22

1908

Participants Needed

1

Research Sites

147 weeks

Total Duration

On this page

Sponsors

U

University of Alabama at Birmingham

Lead Sponsor

U

University Teaching Hospital, Lusaka, Zambia

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if extended admission to the Kangaroo Mother Care (KMC) ward helps to prevent postpartum depression in mothers of low birthweight infants in a low-resource setting whose newborns were admitted to the neonatal intensive care unit (NICU) more than standard of care KMC. The main questions it aims to answer are: * Does longer KMC decrease the incidence of postpartum depression in mothers of low birthweight infants in a low-resource setting? * Does longer KMC improve neurodevelopmental outcomes of low birthweight infants at 6, 12, and 18 months in a low-resource setting? * What are the barriers to practicing KMC in low birthweight infants following hospital discharge in a low-resource setting? * What is the prevalence of paternal depression in a low resource setting? * Is it cost effective to admit preterm mother-infant dyads to the KMC ward following NICU discharge? Researchers will compare (extended admission to the KMC ward) to (standard of care KMC) to see if extended KMC decreases PPD in mothers of preterm infants in low-resource settings. Participants (infants) will: * At time of discharge from the NICU, when clinically stable, spend either \< 2 days in the KMC ward with their mothers or spend longer in the KMC ward until discharge. * Return to clinic at routine follow-up visits (at 2 weeks and at 6-8 weeks) where mothers will be screened for postpartum depression and fathers will be screened for depression. * Return to clinic for neurodevelopmental screening at 6, 12, and 18 months where mothers will be screened for postpartum depression and perceived social support and fathers will be screened for depression.

CONDITIONS

Official Title

Admission to Kangaroo Mother Care (KMC) Ward and Maternal Postpartum Depression

Who Can Participate

Age: 1Day - 89Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Mothers to newborns with birthweight between 1000 and 2000 grams
  • Newborn admitted to NICU for more than 48 hours
  • Stable preterm infants eligible for continuing kangaroo mother care in NICU or at NICU discharge
  • Mothers aged 16 years or older
  • Reside in Lusaka Province with no plans to relocate in the next 18 months
  • Parents (mothers and fathers) of enrolled newborns aged 16 years or older
  • Trusted family members or friends of enrolled newborns aged 18 years or older
  • Fathers of enrolled newborns aged 16 years or older
Not Eligible

You will not qualify if you...

  • Mothers currently receiving treatment for depression or anxiety
  • Mothers who do not consent to participate
  • Underage mothers (16-17 years) without parental consent
  • Family members who do not consent to participate
  • Fathers currently receiving treatment for depression or anxiety
  • Fathers who do not provide informed consent
  • Underage fathers (16-17 years) without parental consent

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Women and Newborn Hospital - University Teaching Hospitals

Lusaka, Zambia, 10101

Actively Recruiting

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Research Team

A

Albert Manasyan, MD, MPH

CONTACT

J

J.Anitha Menon, MA, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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