Study of a Personalized Decision Support Tool to Optimize IVF Drug Dosage for Women with Infertility

What this Trial Is About

Researchers are evaluating the effectiveness of the Opt-IVF decision support tool for personalized drug dosage in women undergoing IVF treatment in the United States. This randomized clinical trial aims to compare outcomes of patients receiving dosages predicted by Opt-IVF against those receiving standard physician-prescribed dosages. The study focuses on whether the Opt-IVF tool can provide better or similar results to current treatments by assessing various fertility outcomes. The trial involves two groups one receiving dosages determined by their doctor as standard practice, and the other receiving dosages recommended by the Opt-IVF tool. The study will monitor treatment cycles and dosage profiles, comparing measures such as the number of mature follicles, total hormone dosages used, and embryo quality. This clinical trial is conducted for research purposes and the decision support tool has not been submitted for regulatory approval. Participants will be monitored closely throughout their stimulation cycles with assessments occurring two to three weeks after the start of treatment. Researchers will measure total hormone dosages, number of oocytes retrieved, mature oocytes, embryos formed, and quality of embryos. Pregnancy rates will be evaluated one month after the first embryo transfer. The trial includes over 100 infertile women undergoing IVF, with careful tracking of treatment outcomes and safety throughout the study period.

An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization for Provera