Actively Recruiting

Age: 18Years - 49Years
All Genders
NCT06539104

Aftificial Inteligence in Assisted Reproductive Techniques to Assess Oocyte Quality and Embryo Ploidy

Led by Charles University, Czech Republic · Updated on 2025-01-22

1000

Participants Needed

4

Research Sites

221 weeks

Total Duration

On this page

Sponsors

C

Charles University, Czech Republic

Lead Sponsor

C

Czech Academy of Sciences

Collaborating Sponsor

AI-Summary

What this Trial Is About

The assisted reproduction success rate is affected by several factors including the age of the women, oocyte quality and maturation state, as well as sperm quality. Imaging of the meiotic spindle may be crucial for determining the oocyte maturation. Artificial intelligence (AI) will be applied to establish the complex oocyte quality, embryo ploidy and pregnancy success probability from the sequence of data, starting with the recording of the meiotic spindle in polarized light, through paternal factors up to the time lapse recording of early embryo development. This strategy should reduce the cost of fertility treatment thanks to increased efficiency in choosing the most promising candidates and reducing the need for costly laboratory analyses.

CONDITIONS

Official Title

Aftificial Inteligence in Assisted Reproductive Techniques to Assess Oocyte Quality and Embryo Ploidy

Who Can Participate

Age: 18Years - 49Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Undergoing intracytoplasmic sperm injection (ICSI)
  • Planned preimplantation genetic testing
  • Availability of time-lapse embryo recording
  • Signed informed consent to participate
Not Eligible

You will not qualify if you...

  • Presence of gynecological diseases
  • Known genetic diseases in either parent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

General University Hospital in Prague

Prague, Czechia, 128 08

Actively Recruiting

2

Czech Technical University in Prague

Prague, Czechia

Actively Recruiting

3

Institute of Physics AS CR

Prague, Czechia

Actively Recruiting

4

Biocev As Cr

Vestec, Czechia

Actively Recruiting

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Research Team

J

Jaromir Masata, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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