Actively Recruiting
Association Between Plasma Level of Mannose Binding Lectin and Human Reproduction
Led by Aalborg University Hospital · Updated on 2025-11-24
500
Participants Needed
1
Research Sites
569 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A low plasma level of mannose binding lectin (p-MBL) is associated with unexplained recurrent pregnancy loss (RPL), but it is not investigated if it is associated with unexplained reproductive failure in general, including recurrent implantation failure (RIF) after assisted reproductive technology (ART) (including IVF, ICSI and FET), recurrent pregnancy loss (RPL) after spontaneous conception, and RPL after ART.
CONDITIONS
Official Title
Association Between Plasma Level of Mannose Binding Lectin and Human Reproduction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women who have had 3 consecutive pregnancy losses after spontaneous conception
- Women who have had 3 consecutive pregnancy losses after assisted reproductive technology (ART) treatment, including IVF, ICSI, and FET
- Women who have had 3 failed embryo transfers with no pregnancy after cycles with at least one good-quality embryo transferred in each cycle
You will not qualify if you...
- Age less than 18 years or greater than 45 years
- Anti-Müllerian hormone (AMH) level less than 4.0 pmol/l unless donor egg was used in previous cycles
- Significant uterine malformation
- Known endometrial conditions such as intrauterine endometriosis, adenomyosis, hyperplasia, or polyps
- Known chromosomal abnormalities
- Pregnancy more than 9 weeks of gestation at the time of blood sample collection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Aagaard Klinik
Aarhus, Denmark, 8200
Actively Recruiting
Research Team
C
Caroline Noergaard-Pedersen, M.D.
CONTACT
O
Ole B. Christiansen
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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