Actively Recruiting
AI-driven Narrow-band Imaging Score for Disease Assessment and Outcome Prediction in Ulcerative Colitis
Led by University College Cork · Updated on 2024-12-03
300
Participants Needed
11
Research Sites
151 weeks
Total Duration
On this page
Sponsors
U
University College Cork
Lead Sponsor
O
Olympus
Collaborating Sponsor
AI-Summary
What this Trial Is About
This international multicentre prospective study aims to develop a new simple score using enhanced endoscopic techniques which focus on the vascular features of the colon and reliably distinguish between a quiescent and a mild inflammation in ulcerative colitis (UC). The diagnostic performance of the new score in defining disease activity/remission compared to existing endoscopic and histological scores and predict long-term clinical outcomes will be evaluated. The study also aims to adapt current artificial intelligence (AI) algorithms for enhanced endoscopic techniques to improve standardization in UC disease assessment and outcome prediction.
CONDITIONS
Official Title
AI-driven Narrow-band Imaging Score for Disease Assessment and Outcome Prediction in Ulcerative Colitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients aged 18 to 75 years old
- Established diagnosis of ulcerative colitis for at least six months
- Undergoing endoscopy for disease activity assessment or cancer surveillance
You will not qualify if you...
- Contraindications to endoscopy or biopsies, including toxic megacolon and severe coagulopathy or thrombocytopenia
- Poor bowel preparation defined as total BBPS score less than 6 or BBPS less than 2 in the observed segment for sigmoidoscopy
- Significant co-morbidities limiting life expectancy or posing high risk for endoscopy
- Pregnant or breastfeeding
- Inability to provide informed consent
- Participation in an experimental trial within the past 30 days
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 11 locations
1
University of Leuven
Leuven, Belgium
Not Yet Recruiting
2
Klinikum Luneburg
Lüneburg, Germany
Not Yet Recruiting
3
University College Cork
Cork, Co Cork, Ireland
Actively Recruiting
4
Ospedale S. Maria del Prato
Feltre, Belluno, Italy
Not Yet Recruiting
5
University of Bari
Bari, Italy
Not Yet Recruiting
6
Istituto Clinico Humanitas
Milan, Italy
Not Yet Recruiting
7
University Vita-Salute San Raffaele
Milan, Italy
Not Yet Recruiting
8
University of Naples
Naples, Italy
Actively Recruiting
9
University of Pavia
Pavia, Italy
Not Yet Recruiting
10
Showa University
Tokyo, Japan
Not Yet Recruiting
11
Changi General Hospital
Singapore, Singapore
Not Yet Recruiting
Research Team
M
Michelle O'Riordan
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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