Actively Recruiting
AI-Enabled Electrocardiogram-Guided Guideline-Directed Medical Therapy on Incident Left Ventricular Dysfunction: A Target Trial Emulation Study
Led by Tri-Service General Hospital · Updated on 2026-01-21
5000
Participants Needed
1
Research Sites
2 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This multicenter retrospective study evaluates whether artificial intelligence-enabled electrocardiography (AI-ECG) can identify individuals at high risk for left ventricular dysfunction and whether targeted guideline-directed medical therapy can mitigate subsequent risk. Using a large multicenter cohort of patients with preserved left ventricular systolic function, the investigators applied an AI-ECG-based risk stratification approach and emulated a target trial to examine the association between guideline-directed therapies and the risk of incident left ventricular functional decline.
CONDITIONS
Official Title
AI-Enabled Electrocardiogram-Guided Guideline-Directed Medical Therapy on Incident Left Ventricular Dysfunction: A Target Trial Emulation Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have an ECG followed by an echocardiogram within 90 days
- Have preserved left ventricular ejection fraction (LVEF ≥ 50%)
You will not qualify if you...
- Missing essential variables or ECG lead data
- Any prior left ventricular ejection fraction below 50%
- Loss to follow-up or death during the 90-day assessment window
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Tri-Service General Hospital
Taipei, Taipei, Taiwan, 11490
Actively Recruiting
Research Team
W
Wei-Ting Liu, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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