Actively Recruiting
Analysis of Articular Biomarkers From Osteoarthritic Thumb Basal Joints
Led by Region Skane · Updated on 2025-06-25
120
Participants Needed
2
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study project aims at examining molecular markers in synovial fluid, bone and articular cartilage from osteoarthritic thumb basal joints. The degradation of extracellular matrix (ECM) proteins in thumb basal joints will be evaluated in association to the metabolic profile of the patient, but we also aim to compare the ECM degradation and inflammatory profiles with articular cartilage degradation ECM profile from knee joints with osteoarthritis. A third aim is to evaluate associations between patient-reported hand function, pain, strength and range of thumb motion to analyses of synovial fluid.
CONDITIONS
Official Title
Analysis of Articular Biomarkers From Osteoarthritic Thumb Basal Joints
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women age 25 25 years
- Radiologically confirmed and symptomatic thumb basal joint osteoarthritis planned for trapeziectomy
You will not qualify if you...
- Previous surgery to the affected thumb basal joint
- Post-traumatic thumb basal joint osteoarthritis
- Rheumatoid arthritis or other chronic inflammatory arthritis, history of psoriasis affecting joints, gout or pseudogout
- Ongoing infection in the hand or wrist
- Inability to cooperate with the follow-up protocol or to understand study information due to language difficulties, severe psychiatric disorder, cognitive impairment, or drug addiction
- Use of systemic or intra-articular glucocorticoids, platelet-rich plasma, or hyaluronic acid injections in the affected joint within 3 months prior to enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Department of Hand Surgery, Skane University Hospital
Malmö, Skåne County, Sweden, 20502
Not Yet Recruiting
2
Aleris Specialistläkare Hyllie
Malmö, Skåne County, Sweden, 21532
Actively Recruiting
Research Team
E
Elisabeth Brogren, MD, PhD
CONTACT
M
My von Walter, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here