Actively Recruiting
A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.
Led by Karolinska Institutet · Updated on 2025-06-03
90
Participants Needed
1
Research Sites
180 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a randomized double-blinded randomized comparison between injection of platelet rich plasma (PRP) and placebo for thumb basale osteoarthritis.
CONDITIONS
Official Title
A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Osteoarthritis in the thumb base
- Radiological Eaton Littler class 1-3
- Clinical signs of thumb base osteoarthritis including pain at palpation of the CMC-1 joint and pain during provocation or grinding test
You will not qualify if you...
- Rheumatoid arthritis
- Ongoing infection in the hand or wrist
- History of gout or pseudogout in the hand
- Inability to co-operate with the follow-up protocol due to language difficulties, severe psychiatric disorder, cognitive impairment, or drug addiction
- Chronic pain syndrome or centralized pain
- Intra-articular injection in the affected joint within 6 months
- Eaton Littler class 4 (symptomatic STT joint osteoarthritis)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Hand Surgery Södersjukhuset
Stockholm, Sweden, S-11883
Actively Recruiting
Research Team
M
Maria Wilcke, MD, PhD
CONTACT
J
Johanna VonKieseritzky, MD. PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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