Actively Recruiting
The Effect of Radiographically Evaluated Anatomical Axis on Pain and Kinesiophobia in Knee Osteoarthritis
Led by Selim Sezikli · Updated on 2026-05-26
100
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Knee osteoarthritis is a common joint disease that causes pain, stiffness, and limits daily activities, especially in older adults. This research aims to explore how changes in the alignment of the lower limb, measured as the anatomical axis on knee X-rays, relate to patients' pain levels, functional abilities, quality of life, and fear of movement (kinesiophobia). The study is observational and cross-sectional, focusing on adult patients diagnosed with knee osteoarthritis. Participants will be adults with knee osteoarthritis who have had a standard anteroposterior knee X-ray taken within the last six months. The study involves no experimental treatment but includes clinical evaluations using validated scales: pain measured by the Visual Analog Scale (VAS), functional status by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), quality of life by the Short Form-36 (SF-36), and kinesiophobia by the Tampa Scale for Kinesiophobia (TSK). Radiographic measurements of the femoro-tibial angle and joint space width will be performed by two independent observers. During the single study visit, participants will complete questionnaires assessing pain, function, quality of life, and fear of movement. Their existing knee X-rays will be reviewed for alignment and joint space. The study will analyze how these radiographic findings relate to clinical symptoms and patient-reported outcomes. No treatment interventions are given, and the study will help to better understand the role of anatomical alignment in knee osteoarthritis management.
CONDITIONS
Brief Title
Anatomical Axis on X-Ray and Its Relationship With Pain and Kinesiophobia in Knee Osteoarthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of knee osteoarthritis (clinical and radiographic)
- An anteroposterior knee X-ray taken within the last 6 months
- Voluntary agreement to participate in the study
- Cognitive ability sufficient to understand test instructions
You will not qualify if you...
- History of knee surgery
- Illiteracy (inability to read or write)
- Refusal to participate
- Presence of orthopedic conditions preventing walking, such as amputation or joint prosthesis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single day assessment
Participants undergo evaluation including clinical assessments of pain, functional status, quality of life, and kinesiophobia using validated scales, along with review of existing knee X-rays taken within the last 6 months.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Istanbul Physical Medicine and Rehabilitation Training and Research Hospital
Istanbul, Turkey (Türkiye), 34186
Actively Recruiting
Research Team
S
Selim Sezikli, MD
C
Cansın Medin Ceylan, Assoc. Prof.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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