Impact of Aortic Valve Disease and Thoracic Aortic Aneurysm on Kinocardiographic Signals

What this Trial Is About

Researchers are exploring kinocardiography (KCG), a portable technique that measures heart mechanical activity by detecting vibrations from heartbeats on the body surface. This study aims to understand KCG signal changes in patients with aortic valve disease (AVD) or thoracic aortic aneurysm (TAA) and to assess if smartphones can help diagnose these conditions. The study compares KCG signals with echocardiography, cardiac MRI, phonocardiography (PCG), and video recordings in affected patients and healthy individuals. Participants include patients with severe AVD or TAA scheduled for interventional treatment, those with varying severities of AVD, and healthy controls matched by age, sex, body surface area, and heart function. After clinical imaging (echocardiography or MRI), researchers record KCG and PCG data using sensors on the chest and back and perform similar measurements with a smartphone. Video recordings are taken alongside KCG signals. For patients undergoing surgery, post-operative KCG and imaging measurements are also collected. Participants will attend sessions coinciding with their clinical imaging appointments, during which multiple recordings (KCG, PCG, video) are made. Researchers will analyze these data to understand KCG signal modifications related to AVD and TAA, comparing them with clinical assessments. The study also evaluates the potential of smartphone-based measurements for diagnosis. The main outcome is to clarify the mechanisms behind KCG changes over 12 months, with additional assessments over 18 months.

Aortopathy Relationship To Imagery and Kinocardiography Features (ARTIK)