AI-CARE Study Evaluating Aorta AIM Artificial Intelligence Software for Automated Aortic Measurement Using CT Scans

What this Trial Is About

Researchers are evaluating the accuracy and efficiency of an artificial intelligence AI software called Aorta AIM in measuring the size of the aorta, the bodys main blood vessel, using CT scans. The study focuses on comparing Aorta AIMs automated measurements with those made manually by experienced radiologists or cardiologists. This research aims to improve how doctors monitor aortic enlargement, which can lead to serious health problems, by providing a consistent and faster measurement method. The study involves retrospectively collecting chest or abdominal CT scans from adults aged 22 and older taken as part of routine medical care between January 1, 2016, and August 31, 2025. These scans will be analyzed by both the Aorta AIM software and expert radiologists who manually measure aortic diameters. The software provides standardized measurements at specific anatomical locations, and any discrepancies between manual readers are resolved by a senior expert for an accurate reference standard. Participants have already undergone CT imaging, so no additional scans or procedures are required. Researchers will review the collected data to compare measurement accuracy, processing time, and clinical acceptability of the AI software against expert assessments. The main outcome is the average difference between AI and expert measurements. Secondary outcomes include agreement limits, measurement reliability, software yield, processing speed, and expert clinical acceptability scores. The study includes about 250 participants from multiple hospitals, with no risks since only existing images are used.

AI-CARE: Artificial Intelligence for Cardiovascular Analysis and Risk Evaluation