Actively Recruiting

Phase 2
Age: 18Years +
All Genders
ID05761366

Use of Al18F-PSMA-BCH PET/CT Imaging to Detect Prostate Specific Membrane Antigen Positive Tumors Including Prostate and Other Cancers

Led by Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Updated on 2024-12-27

400

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the tumor detection ability of Al18F-PSMA-BCH PET/CT imaging in patients who have tumors expressing prostate specific membrane antigen (PSMA). These tumors include prostate cancer, transitional epithelial carcinoma, colon carcinoma, adenoid cystadenocarcinoma, mesothelioma, hepatocellular carcinoma, cholangiocellular carcinoma, multiple myeloma, and others. The study is a Phase 2 clinical trial focused on assessing the effectiveness of this imaging technique in detecting these specific tumors. Participants will receive an intravenous injection of the Al18F-PSMA-BCH tracer followed by a PET/CT scan to visualize PSMA positive tumors. This imaging procedure is used to detect and evaluate the presence of tumors expressing PSMA. The study involves only this intervention without comparison groups, focusing on the diagnostic performance of Al18F-PSMA-BCH PET/CT. During the study, participants will undergo the PET/CT scan after tracer injection. Researchers will monitor the diagnostic value of the imaging throughout the study period, which averages about 1 year. Participants must cooperate with all study procedures and provide informed consent. Safety and diagnostic results will be observed and evaluated to determine how well the imaging detects PSMA positive tumors.

CONDITIONS

Official Title

Application of 18F-PSMA PET / CT Imaging in Prostate Specific Membrane Antigen Positive Tumor

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with suspected or confirmed PSMA positive-expressing tumors including prostate cancer, transitional epithelial carcinoma, colon carcinoma, adenoid cystadenocarcinoma, mesothelioma, hepatocellular carcinoma, cholangiocellular carcinoma, multiple myeloma, and others
  • Age 18 years or older
  • No gender restrictions
  • Signed informed consent
  • Willing and able to cooperate with all study procedures
Not Eligible

You will not qualify if you...

  • Serious neurological, gastrointestinal, cardiovascular, liver, kidney, blood, endocrine, respiratory, or immune deficiency diseases
  • Claustrophobia
  • Pregnant or breastfeeding women
  • Received experimental drug or device within the past 1 month

AI-Screening

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Trial Site Locations

Total: 1 location

1

National Cancer Center/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College

Beijing, Chaoyang, China, 100029

Actively Recruiting

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Research Team

X

Xin Cheng, MD

G

Guozhu Hou, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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