Actively Recruiting
Arterial Stiffening as a Predictor for Diastolic Cardiac Dysfunction and HFpEF
Led by University Medical Center Goettingen · Updated on 2024-05-09
150
Participants Needed
1
Research Sites
201 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients at risk for developing heart failure with preserved ejection fraction (HFpEF) will undergo a structured clinical assessment, transthoracic echocardiography and pulse-wave analysis to investigate the association of arterial stiffening and the development of cardiac diastolic dysfuntion and HFpEF.
CONDITIONS
Official Title
Arterial Stiffening as a Predictor for Diastolic Cardiac Dysfunction and HFpEF
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than 60 years
- Arterial hypertension (systolic blood pressure 2140 mmHg or diastolic 290 mmHg or use of 2 or more antihypertensive drugs)
- Diabetes mellitus type I or II
- Atrial fibrillation
- Chronic kidney disease (glomerular filtration rate less than 60 ml/min/1.73 m2 or urine albumin 230 mg/24h or albumin-to-creatinine ratio 230 mg/g)
- Body mass index (BMI) of 30 kg/m2 or greater
- New York Heart Association (NYHA) functional class II or higher
- E/e' ratio greater than 8
You will not qualify if you...
- Left ventricular ejection fraction less than 50%
- Significant valve disease of grade III or higher
- History of interventional or surgical valve repair
- Regional wall motion abnormalities
- Respiratory diseases known to cause shortness of breath
- Atrial flutter or fibrillation during examination
- Hypertrophic, restrictive, arrhythmogenic, or dilated cardiomyopathies including cardiac amyloidosis or sarcoidosis and toxic cardiomyopathy
- History of heart transplantation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Universitätsmedizin Göttingen
Göttingen, Lower Saxony, Germany, 37075
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here