Actively Recruiting

Age: 40Years - 75Years
All Genders
ID07257796

Artificial Intelligence in Assessing Gastric Intestinal Metaplasia Via the EGGIM Score

Led by Qilu Hospital of Shandong University · Updated on 2025-12-02

3000

Participants Needed

3

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate an artificial intelligence (AI) system designed to automatically assess the extent of gastric intestinal metaplasia (GIM) during endoscopy by calculating the EGGIM scores. Gastric intestinal metaplasia is an important precancerous condition, and the study seeks to validate the accuracy, performance, and reliability of this AI-assisted scoring method in a prospective, multi-center setting. Participants will undergo an image-enhanced endoscopy (IEE) examination, where both experienced endoscopists and the AI system independently assess the extent of GIM using the EGGIM score. This study builds on prior preliminary research and aims to confirm the AI system's diagnostic performance compared to human experts. During the study, patients aged 40 to 75 years who consent to participate will have their endoscopic images evaluated by both the AI and the endoscopists. The main outcome measured is how well the AI system diagnoses the grade of intestinal metaplasia by calculating the EGGIM score within one year. This observational study involves no experimental treatments, focusing on diagnostic evaluation and data collection over the study period.

CONDITIONS

Brief Title

Artificial Intelligence in Assessing Gastric Intestinal Metaplasia Via the EGGIM Score

Who Can Participate

Age: 40Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 40 to 75 years undergoing image-enhanced endoscopy (IEE) examination
  • Patients who voluntarily sign the informed consent form
Not Eligible

You will not qualify if you...

  • Patients with severe cardiac, cerebral, pulmonary, or renal dysfunction or psychiatric disorders unable to undergo gastroscopy
  • Patients with previous surgical procedures on the stomach

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 day

Participants undergo image-enhanced endoscopy where both endoscopists and the AI system independently assess the extent of gastric intestinal metaplasia using the EGGIM score.

1 visit (in-person)

Long-term Monitoring

Duration - 1 year

Participants are followed for up to 1 year to evaluate the performance of the AI system in diagnosing the grade of intestinal metaplasia.

Visits as per routine clinical care

Trial Site Locations

Total: 3 locations

1

Qilu Hospital of Shandong University

Jinan, Shandong, China, 250012

Actively Recruiting

2

Shandong First Medical University First Affiliated Hospital

Jinan, Shandong, China

Not Yet Recruiting

3

Shandong Second Provincial General Hospital

Jinan, Shandong, China

Not Yet Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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