Actively Recruiting

Age: 18Years +
All Genders
ID05176769

The Usefulness of Artificial Intelligence for Automated Extraction and Processing of Clinical Data From Electronic Medical Records (CardioMining-AI)

Led by AHEPA University Hospital · Updated on 2025-01-29

60000

Participants Needed

9

Research Sites

12 weeks

Total Duration

On this page

Sponsors

A

AHEPA University Hospital

Lead Sponsor

H

Hippokration Hospital Athens

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the usefulness of artificial intelligence (AI) and machine learning to develop computer algorithms that can quickly and accurately extract and process large amounts of clinical data from electronic medical records. This study focuses on hospitalized cardiology patients in Greece and aims to improve automated data analysis, early disease diagnosis, and the development of clinical decision support systems. The study also plans to develop prognostic models for major cardiovascular diseases using AI methods. The study will retrospectively collect electronically registered clinical notes, laboratory results, and imaging exams from about 60,000 patients hospitalized in cardiology wards. Personal identifying information will be removed to protect privacy. Initially, clinical notes will be manually analyzed to create a database and identify keywords for diagnoses. Then, AI techniques, including natural language processing, will be used to automatically extract data from the remaining notes. The accuracy and reliability of these automated methods will be compared with manual extraction for evaluation. Participants' data will be analyzed over time, with primary outcomes measuring the accuracy of AI-based data extraction compared to manual methods within one year. Secondary outcomes include tracking times to events such as death, major cardiovascular disease incidents, rehospitalization, stroke, and acute coronary syndrome over up to eight years from hospital discharge. The study aims to improve how clinical data is processed and used for patient care and research without interfering with usual medical treatment.

CONDITIONS

Brief Title

Artificial Intelligence for Automated Clinical Data Exploration From Electronic Medical Records (CardioMining-AI)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Hospitalised patients in Cardiology Departments in Greece
  • Patients whose medical records are electronically stored in each hospital's computer/information systems
  • Adults aged 18 years or older
Not Eligible

You will not qualify if you...

  • Patients that died during hospitalization, and thus no discharge letter was issued

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote review)

Diagnostic Evaluation

Duration - Retrospective from hospitalizations over multiple years

Participants' electronic medical records are collected and manually analyzed to extract clinical data and diagnoses.

No participant visits required; data collection is retrospective

Long-term Monitoring

Duration - Up to 8 years from hospital discharge

Participants' clinical data are monitored over time using artificial intelligence methods to evaluate accuracy and track health outcomes such as mortality and cardiovascular events.

No participant visits required; monitoring is conducted via electronic records

Trial Site Locations

Total: 9 locations

1

University Cardiology Clinic, Democritus University of Thrace

Alexandroupoli, Greece

Not Yet Recruiting

2

1st Department of Cardiology, Hippokration General Hospital

Athens, Greece

Actively Recruiting

3

Department of Cardiology, Heraklion University Hospital

Heraklion, Greece

Not Yet Recruiting

4

University General Hospital of Larissa, University of Thessaly

Larissa, Greece

Actively Recruiting

5

Department of Cardiology, University of Patras Medical School

Pátrai, Greece

Actively Recruiting

6

1st Cardiology Department, AHEPA University Hospital

Thessaloniki, Greece, 54636

Actively Recruiting

7

3rd Cardiology Department, Hippokration Hospital

Thessaloniki, Greece

Not Yet Recruiting

8

Cardiology Department, George Papanikolaou General Hospital

Thessaloniki, Greece

Actively Recruiting

9

Laboratory of Medical Physics, Aristotle University of Thessaloniki

Thessaloniki, Greece

Actively Recruiting

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Research Team

G

George Giannakoulas, MD, PhD

A

Athanasios Samaras, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Published Research Related To This Trial

Machine learning algorithms estimating prognosis and guiding therapy in adult congenital heart disease: data from a single tertiary centre including 10 019 patients.

Gerhard-Paul Diller, Aleksander Kempny, Sonya V Babu-Narayan...

https://pubmed.ncbi.nlm.nih.gov/30689812

Artificial intelligence-based mining of electronic health record data to accelerate the digital transformation of the national cardiovascular ecosystem: design protocol of the CardioMining study.

Athanasios Samaras, Alexandra Bekiaridou, Andreas S Papazoglou...

https://pubmed.ncbi.nlm.nih.gov/37012018