Artificial Intelligence in Cardiology.
Kipp W Johnson, Jessica Torres Soto, Benjamin S Glicksberg...
https://pubmed.ncbi.nlm.nih.gov/29880128Actively Recruiting
Led by AHEPA University Hospital · Updated on 2025-01-29
60000
Participants Needed
9
Research Sites
12 weeks
Total Duration
A
AHEPA University Hospital
Lead Sponsor
H
Hippokration Hospital Athens
Collaborating Sponsor
Researchers are evaluating the usefulness of artificial intelligence (AI) and machine learning to develop computer algorithms that can quickly and accurately extract and process large amounts of clinical data from electronic medical records. This study focuses on hospitalized cardiology patients in Greece and aims to improve automated data analysis, early disease diagnosis, and the development of clinical decision support systems. The study also plans to develop prognostic models for major cardiovascular diseases using AI methods. The study will retrospectively collect electronically registered clinical notes, laboratory results, and imaging exams from about 60,000 patients hospitalized in cardiology wards. Personal identifying information will be removed to protect privacy. Initially, clinical notes will be manually analyzed to create a database and identify keywords for diagnoses. Then, AI techniques, including natural language processing, will be used to automatically extract data from the remaining notes. The accuracy and reliability of these automated methods will be compared with manual extraction for evaluation. Participants' data will be analyzed over time, with primary outcomes measuring the accuracy of AI-based data extraction compared to manual methods within one year. Secondary outcomes include tracking times to events such as death, major cardiovascular disease incidents, rehospitalization, stroke, and acute coronary syndrome over up to eight years from hospital discharge. The study aims to improve how clinical data is processed and used for patient care and research without interfering with usual medical treatment.
CONDITIONS
Artificial Intelligence for Automated Clinical Data Exploration From Electronic Medical Records (CardioMining-AI)
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person or remote review)
Duration - Retrospective from hospitalizations over multiple years
Participants' electronic medical records are collected and manually analyzed to extract clinical data and diagnoses.
No participant visits required; data collection is retrospective
Duration - Up to 8 years from hospital discharge
Participants' clinical data are monitored over time using artificial intelligence methods to evaluate accuracy and track health outcomes such as mortality and cardiovascular events.
No participant visits required; monitoring is conducted via electronic records
Total: 9 locations
1
University Cardiology Clinic, Democritus University of Thrace
Alexandroupoli, Greece
Not Yet Recruiting
2
1st Department of Cardiology, Hippokration General Hospital
Athens, Greece
Actively Recruiting
3
Department of Cardiology, Heraklion University Hospital
Heraklion, Greece
Not Yet Recruiting
4
University General Hospital of Larissa, University of Thessaly
Larissa, Greece
Actively Recruiting
5
Department of Cardiology, University of Patras Medical School
Pátrai, Greece
Actively Recruiting
6
1st Cardiology Department, AHEPA University Hospital
Thessaloniki, Greece, 54636
Actively Recruiting
7
3rd Cardiology Department, Hippokration Hospital
Thessaloniki, Greece
Not Yet Recruiting
8
Cardiology Department, George Papanikolaou General Hospital
Thessaloniki, Greece
Actively Recruiting
9
Laboratory of Medical Physics, Aristotle University of Thessaloniki
Thessaloniki, Greece
Actively Recruiting
G
George Giannakoulas, MD, PhD
A
Athanasios Samaras, MD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Kipp W Johnson, Jessica Torres Soto, Benjamin S Glicksberg...
https://pubmed.ncbi.nlm.nih.gov/29880128Chayakrit Krittanawong, HongJu Zhang, Zhen Wang...
https://pubmed.ncbi.nlm.nih.gov/28545640Ali Madani, Ramy Arnaout, Mohammad Mofrad...
https://pubmed.ncbi.nlm.nih.gov/30828647Willie Boag, Dustin Doss, Tristan Naumann...
https://pubmed.ncbi.nlm.nih.gov/29888035Mohammad Hashir, Rapinder Sawhney
https://pubmed.ncbi.nlm.nih.gov/32592755Gerhard-Paul Diller, Aleksander Kempny, Sonya V Babu-Narayan...
https://pubmed.ncbi.nlm.nih.gov/30689812Athanasios Samaras, Alexandra Bekiaridou, Andreas S Papazoglou...
https://pubmed.ncbi.nlm.nih.gov/37012018