Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06629207

Artificial Intelligence in Molecular Imaging: Predicting Parkinson's Risk in REM Sleep Behavior Disorder

Led by Insel Gruppe AG, University Hospital Bern · Updated on 2024-11-08

20

Participants Needed

1

Research Sites

94 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study aims to systematically document the course of REM sleep behavior disorder (RBD) and investigate possible clinical and imaging biomarkers for disease progression and conversion risk to Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). The study will use artificial intelligence to analyze imaging and develop a reliable method to predict and stratify patients approaching conversion to overt a-synucleinopathy. Participants will be clinically evaluated and 2 imaging procedures will be done.

CONDITIONS

Official Title

Artificial Intelligence in Molecular Imaging: Predicting Parkinson's Risk in REM Sleep Behavior Disorder

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed diagnosis of isolated REM sleep behavior disorder by movement disorder specialists based on International Classification of Sleep Disorders
  • Written informed consent provided
Not Eligible

You will not qualify if you...

  • Known diagnosis of Parkinson's disease or other neurodegenerative disorders
  • Clear signs of parkinsonism on examination
  • Narcolepsy or other known causes of REM sleep behavior disorder
  • Moderate to severe obstructive sleep apnea
  • Abnormal neurological or MRI examination findings

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Inselspital, University Clinic for Nuclear Medicine

Bern, Switzerland, 3010

Actively Recruiting

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Research Team

A

Axel Rominger, Prof. Dr. med.

CONTACT

F

Franziska Strunz, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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