Actively Recruiting

Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT07394998

Assessment of Exercise Capacity, Muscle Oxygenation and Aortic Stiffness in Patients With Mitral Stenosis

Led by Gazi University · Updated on 2026-02-06

40

Participants Needed

1

Research Sites

76 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Heart valve diseases are the most common cause of mortality and morbidity after coronary artery disease, hypertension, and heart failure. In patients with mitral stenosis, the narrowed valve restricts blood flow, causing symptoms such as shortness of breath, fatigue, exertional dyspnea, orthopnea, and paroxysmal nocturnal dyspnea. These patients may experience decreased exercise capacity and physical activity levels, deterioration in quality of life, and deterioration in respiratory function. When reviewing the literature, we see that the study groups evaluating these factors are generally not homogeneous, and most studies conducted in patients with mitral stenosis evaluate patients who have undergone percutaneous mitral balloon valvuloplasty.

CONDITIONS

Official Title

Assessment of Exercise Capacity, Muscle Oxygenation and Aortic Stiffness in Patients With Mitral Stenosis

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged between 18 and 80 years
  • Patients who have undergone mitral valve intervention for mitral stenosis
  • At least 3 months have passed since the mitral valve intervention
  • Healthy volunteers aged between 18 and 80 years
  • Healthy volunteers who agree to participate voluntarily
Not Eligible

You will not qualify if you...

  • Patients who have had aortic valve intervention other than mitral valve intervention
  • Patients with acute infection
  • Patients with orthopedic, neurological, or psychological disorders affecting functional capacity
  • Healthy volunteers diagnosed with chronic disease
  • Healthy volunteers with acute infection
  • Healthy volunteers with a smoking history of at least 10 pack-years

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Gazi University Faculty of Health Sciences Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Unit

Ankara, Çankaya, Turkey (Türkiye), 06490

Actively Recruiting

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Research Team

M

Meral BOŞNAK GÜÇLÜ, Prof. Dr.

CONTACT

E

Ebrar TÜLÜMENOĞLU, Pt

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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