Evaluating Hemodynamic Changes Using Bispectral Index Monitoring During Rapid Sequence Intubation in Emergency Department Patients

What this Trial Is About

This research aims to evaluate the hemodynamic responses, such as changes in heart rate and blood pressure, during rapid sequence intubation RSI in critically ill adult patients in the emergency department. The study focuses on patients who have an adequate depth of anesthesia confirmed by bispectral index BIS monitoring before laryngoscopy, addressing a gap in emergency settings where previous evidence is limited. Participants undergo RSI while BIS monitoring is used to confirm sufficient anesthesia depth BIS value between 45 and 55 before the procedure. Heart rate and blood pressure are recorded at multiple time points before induction, during intubation, immediately after intubation, and at 5, 10, and 15 minutes post-intubation. The study is observational and does not involve additional treatments beyond standard emergency care. During the study, participants will have their vital signs closely monitored using BIS devices and standard hemodynamic measures. Researchers will collect data on blood pressure and heart rate changes to objectively assess the cardiovascular response to the intubation process. The study requires informed consent and excludes certain populations such as those requiring immediate intubation or with technical issues preventing BIS use. The total participation duration varies with the procedure and monitoring schedule.

Assessment of Hemodynamic Responses at Adequate Depth of Anesthesia Using Bispectral Index During Rapid Sequence Intubation in the Emergency Department