Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT05414994

Assessment of the Ocular Microbiome in Health and Disease

Led by Vanderbilt University Medical Center · Updated on 2026-01-22

500

Participants Needed

1

Research Sites

225 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of this application is to illustrate the core constituents of the ocular surface microbiome, describe factors that promote colonization, and assess the ocular microbiome's role in the health of the anterior segment. We will conduct a prospective, observational cohort study, including a longitudinal analysis of the ocular microbiome in adults.

CONDITIONS

Official Title

Assessment of the Ocular Microbiome in Health and Disease

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Provide informed consent
  • Normal eyes with no ocular disease (Cohort A)
  • Mild primary open angle glaucoma or ocular hypertension controlled with no more than one prostaglandin drop daily for the past 6 months (Cohort B)
  • Non-infectious keratopathy without use of prescription medication (over-the-counter artificial tears allowed) (Cohort C)
  • Dry age-related macular degeneration (Cohort D)
  • Wet age-related macular degeneration (Cohort E)
  • Diabetic retinopathy (Cohort F)
Not Eligible

You will not qualify if you...

  • Prior ocular disease of the anterior or posterior segment
  • Any medical comorbidities except well-controlled diabetes and hypertension
  • Inability to follow up with study procedures as described

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37232

Actively Recruiting

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Research Team

H

Havin Abdulkadir

CONTACT

S

Saige Priddy

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

6

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Assessment of the Ocular Microbiome in Health and Disease | DecenTrialz