Study of Ultrasound Findings and Relapse in Adults with Giant Cell Arteritis

What this Trial Is About

Researchers are evaluating the link between ultrasound-detected lesions in temporal and axillary arteries and relapse in patients with giant cell arteritis, a disease affecting medium and large blood vessels. This prospective, bicentric longitudinal observational study aims to understand how ultrasound abnormalities relate to disease relapse and clinical outcomes, using the OGUS score as a predictive tool. The study involves patients routinely monitored for giant cell arteritis who receive temporal artery ultrasound as part of their standard care. There are no additional interventions or treatments, as this is a non-interventional study. Participants will undergo three visits including clinical, biological, and ultrasound assessments over the course of their routine follow-up. Participants will have clinical examinations, blood tests including C-Reactive Protein and Sedimentation Rate, and ultrasound imaging at baseline, 6 months, and 12 months. Researchers will track relapse based on EULAR 2018 criteria at 6 and 12 months, along with various clinical and biological markers. The study includes no extra costs or constraints and aims to follow patients for up to 12 months after enrollment.

Association of Ultrasonographic Temporal Artery Lesions and Relapse in Patients With Giant Cell Arteritis