Actively Recruiting
Avacostar - (PASS)
Led by Vifor Fresenius Medical Care Renal Pharma · Updated on 2025-01-31
500
Participants Needed
35
Research Sites
376 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The Avacostar PASS is a non-interventional, multi-national, prospective cohort study that will collect data from 2 cohorts of patients: those treated with avacopan for active severe AAV, and a second cohort treated with a cyclophosphamide or rituximab-based induction regimen without avacopan for active severe AAV. The overall study duration is anticipated to be up to 7 years, including a recruitment period of approximately 3 years.
CONDITIONS
Official Title
Avacostar - (PASS)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of ANCA-associated vasculitis (MPA or GPA) as determined by the Investigator.
- Active, severe AAV when starting avacopan or standard induction therapy.
- Age 18 years or older, any sex.
- Provided written informed consent.
- Started or planned to start avacopan, cyclophosphamide, or rituximab within the last 6 months for severe active AAV outside an interventional study.
You will not qualify if you...
- Concurrent participation in an interventional study unless approved by the Medical Monitor.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 35 locations
1
Charité University Medicine
Berlin, Germany
Actively Recruiting
2
University Hospital of Cologne
Cologne, Germany
Actively Recruiting
3
Municipal Hospital Dresden
Dresden, Germany
Not Yet Recruiting
4
University Hospital Essen
Essen, Germany
Actively Recruiting
5
University Hospital Freiburg
Freiburg im Breisgau, Germany
Actively Recruiting
6
University Medical Center Göttingen
Göttingen, Germany
Actively Recruiting
7
University Hospital Eppendorf
Hamburg, Germany
Not Yet Recruiting
8
KRH Klinikum Siloah
Hanover, Germany
Actively Recruiting
9
Rheumazentrum Ruhrgebiet
Herne, Germany
Actively Recruiting
10
LMU
Munich, Germany
Not Yet Recruiting
11
Medius Kliniken
Plochingen, Germany
Actively Recruiting
12
St. Josef-Stift Sendenhorst
Sendenhorst, Germany
Not Yet Recruiting
13
UHB NHS Foundation Trust
Birmingham, United Kingdom
Actively Recruiting
14
Bradford Teaching Hospitals NHS Foundation Trust
Bradford, United Kingdom
Actively Recruiting
15
North Bristol NHS Trust
Bristol, United Kingdom
Actively Recruiting
16
Addenbrookes Hospital
Cambridge, United Kingdom
Actively Recruiting
17
East Kent Hospitals University NHS FT
Canterbury, United Kingdom
Actively Recruiting
18
Cardiff and Vale UHB
Cardiff, United Kingdom
Actively Recruiting
19
Epsom & St. Helier NHS Trust
Carshalton, United Kingdom
Actively Recruiting
20
University Hospitals Coventry and Warwickshire
Coventry, United Kingdom
Actively Recruiting
21
Royal Devon University Healthcare NHS Foundation Trust
Exeter, United Kingdom
Actively Recruiting
22
NHS Greater Glasgow & Clyde
Glasgow, United Kingdom
Actively Recruiting
23
University Hospitals of Leicester NHS Trust
Leicester, United Kingdom
Actively Recruiting
24
Barts Health
London, United Kingdom
Actively Recruiting
25
Hammersmith Hospital, Imperial College Healthcare NHS Trust
London, United Kingdom
Actively Recruiting
26
Kings College Hospital
London, United Kingdom
Actively Recruiting
27
Royal Free
London, United Kingdom
Actively Recruiting
28
St Thomas' Hospital
London, United Kingdom
Actively Recruiting
29
Manchester University NHS Foundation Trust
Manchester, United Kingdom
Actively Recruiting
30
Nottingham university hospitals NHS trust
Nottingham, United Kingdom
Actively Recruiting
31
Rheumatology Department, Oxford University Hospitals NHS Foundation Trust
Oxford, United Kingdom
Actively Recruiting
32
Royal Berkshire NHS foundation trust
Reading, United Kingdom
Actively Recruiting
33
Northern Care Alliance
Salford, United Kingdom
Actively Recruiting
34
Swansea Bay University LHB
Swansea, United Kingdom
Actively Recruiting
35
York & Scarborough Teaching Hospitals NHS FT
York, United Kingdom
Actively Recruiting
Research Team
A
Avacostar Study Team
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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