Biocollection of Patients With ANCA Associated Vasculitis Diagnosed Within the CERAINO Autoimmune Disease Reference Center, Part of the Global BRAISE Project

What this Trial Is About

Researchers are studying ANCA-associated vasculitis, a group of rare and serious autoimmune diseases including granulomatosis with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis. The goal is to understand the disease better by collecting standardized data over several years, focusing mainly on identifying predictors of relapse and other complications like mortality, infections, cardiovascular issues, and cancer to improve patient care. Participants with ANCA-associated vasculitis will be part of a single study group undergoing various sample collections and assessments. These include blood samples, fecal samples, and urinary samples taken at the start, annually for five years, and during any relapse or treatment change. Questionnaires will also be completed at these times to gather patient-reported information. During the study, participants will be monitored for disease relapse and other health outcomes over five years. Researchers will use tools like the Birmingham Vasculitis Activity Score and Vasculitis Damage Index to assess disease activity and damage, alongside patient and physician evaluations. Safety and treatment effects, including the impact of glucocorticoids, will be tracked, with study visits involving sample collection and questionnaires to help understand disease progression and patient health over time.

Biocollection of Patients With ANCA Associated Vasculitis