Unusual Triggering of the Finger Caused by Distal Flexor Tendinopathy: Successful Treatment With Ultrasound-Guided Prolotherapy.
Yonghyun Yoon, Ji Hyo Hwang, Jaeyoung Lee...
https://pubmed.ncbi.nlm.nih.gov/41555987/Actively Recruiting
Led by Istanbul University - Cerrahpasa · Updated on 2026-07-28
42
Participants Needed
1
Research Sites
4 weeks
Total Duration
This research aims to compare the effectiveness of ultrasound-guided betamethasone and dextrose injections in adults with trigger finger, a condition causing pain, clicking, and locking of the finger due to tendon entrapment. While corticosteroid injections like betamethasone are commonly used first-line treatments, they can have side effects. Dextrose injections are being studied as a possible alternative that may help tissue healing, but evidence for their effectiveness in trigger finger is limited. Participants will be randomly assigned to receive one of two ultrasound-guided injections at the A1 pulley either 1 ml lidocaine with 1 ml betamethasone or 1 ml lidocaine with 1 ml 30% dextrose solution diluted to 15% dextrose. All injections are performed under sterile conditions. The study uses a triple-blind design where the injector, participant, and assessor are unaware of the treatment given. Participants will be assessed at baseline, 1 hour, 2 weeks, 4 weeks, and 12 weeks after injection. Researchers will measure pain intensity using the Numeric Rating Scale as the primary outcome. Secondary outcomes include severity of triggering, hand function, grip and pinch strength, and fine motor skills. These evaluations aim to determine whether dextrose injections can serve as a safe and effective alternative to corticosteroids for treating trigger finger.
CONDITIONS
Betamethasone vs Dextrose Injections in Trigger Finger
M
Merve Yıldız, MD
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Istanbul University - Cerrahpasa
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening visit
Duration - 12 weeks
Participants receive an ultrasound-guided injection of either betamethasone or dextrose at the A1 pulley level to treat trigger finger.
Visits at baseline, 1 hour, 2 weeks, 4 weeks, and 12 weeks post-injection
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Yonghyun Yoon, Ji Hyo Hwang, Jaeyoung Lee...
https://pubmed.ncbi.nlm.nih.gov/41555987/Ding-Hao Liu, Mei-Wun Tsai, Shan-Hui Lin...
https://pubmed.ncbi.nlm.nih.gov/26340807/Istanbul University - Cerrahpasa
Lead Sponsor