Actively Recruiting

Age: 18Years +
All Genders
NCT06318598

Biomarker-driven Phenotypic Dissection of Amyotrophic Lateral Sclerosis

Led by Istituto Auxologico Italiano · Updated on 2025-05-07

200

Participants Needed

3

Research Sites

156 weeks

Total Duration

On this page

Sponsors

I

Istituto Auxologico Italiano

Lead Sponsor

A

A.O.U. Città della Salute e della Scienza

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to understand the clinical variability in a population of ALS patients using multidimensional biomarkers. The main questions it aims to answer are: * Which set of biomarkers explain genotypic-phenotypic correlations in ALS? * Which set of biomarkers can be used to subdivide the ALS population in homogeneous subgroups? Participants will undergo: * neurological evaluation * neurophysiological evaluation * neuropsychological evaluation * whole exome sequencing * biomarker measurement in CSF and plasma

CONDITIONS

Official Title

Biomarker-driven Phenotypic Dissection of Amyotrophic Lateral Sclerosis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of ALS or other motor neuron disease
  • Residence near the study centers
Not Eligible

You will not qualify if you...

  • Refusal to participate in the study
  • Unable or unwilling to perform follow-up visits

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Ospedale San Raffaele

Milan, MI, Italy, 20132

Actively Recruiting

2

Ospedale San Luca

Milan, MI, Italy, 20149

Actively Recruiting

3

AOU Città della Salute e della Scienza

Torino, TO, Italy, 10126

Actively Recruiting

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Research Team

N

Nicola Ticozzi, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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