Study of Telephone-Based Cognitive Screening in Adults with Neurological Disorders and Healthy Individuals in Italy

What this Trial Is About

Researchers are evaluating telephone-based cognitive screening tests in people with chronic neurological disorders such as amyotrophic lateral sclerosis, Alzheimers disease, Lewy body dementia, frontotemporal dementia, and chronic cerebrovascular disorders. This observational study conducted in Italy aims to assess the reliability, diagnostic accuracy, and clinical usefulness of these telephone tests, which may help overcome barriers to access and support decentralized research and care. The study also seeks to establish normative data and conversion tools for in-person and telephone cognitive assessments in healthy individuals. Participants include patients with specific neurological diagnoses and a group of healthy individuals representative of the Italian population. Patients will undergo several telephone-based cognitive and behavioral tests, while healthy participants will receive both telephone and in-person cognitive assessments. Follow-up telephone evaluations for patients are planned at 6, 12, and 18 months to track changes over time. The study uses established clinical questionnaires and scales to evaluate daily functioning and behavioral symptoms. Throughout the study, participants will complete cognitive screening tests, caregiver-reported questionnaires, and standard assessments such as the Mini-Mental State Examination and Montreal Cognitive Assessment. Researchers will analyze the phone-based tests psychometric properties and clinical usefulness over repeated sessions. The total study duration includes initial enrollment and follow-up assessments up to 18 months, providing data on the tests performance and applicability in real-world clinical and research settings.

Advances in Telephone-based Cognitive Screening Procedures