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Study of Blood, Urine, and Tissue Biomarkers in Kidney Disease Before and After Kidney Transplantation for Diagnosis and Prognosis
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-02-05
1000
Participants Needed
1
Research Sites
52 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating the use of blood, urine, and tissue biomarkers to diagnose and predict kidney diseases, including conditions affecting native kidneys and kidney transplant recipients. This observational study aims to improve understanding of these diseases and help identify markers that could lead to earlier, more personalized treatment, potentially improving long-term kidney graft survival. Participants include patients undergoing kidney biopsy or kidney transplantation. Samples of blood about 17.5 mL, urine 50 to 100 mL, and tissue from biopsies will be collected during routine care visits. These samples may be stored for genetic studies. For kidney transplant patients, blood and urine samples are taken on the day of the kidney biopsy. Participants will have clinical data recorded from routine care, including demographic, biological, clinical, and imaging information. Samples will be collected once during treatment visits. The main outcome is to identify diagnostic and prognostic biomarkers over one year. The study will monitor disease progression and the role of biomarkers in kidney health without influencing standard care.
CONDITIONS
Brief Title
BIOmarkers Before and After Kidney Transplantation
Research Team
M
Marie Dr MATIGNON, MD, PhD
V
Vincent Pr AUDARD, MD, PhD
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