Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT07578610

Biomedical Signal Extraction From Symptom Descriptions: An Observational Registry Using the OpenGenome Platform

Led by OpenGenome · Updated on 2026-05-13

1000

Participants Needed

1

Research Sites

108 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This registry prospectively collects anonymized free-text symptom descriptions submitted voluntarily by adults through the OpenGenome platform at opengenome.bio. For each submission, the system retrieves real biomedical literature from PubMed and ClinicalTrials.gov in parallel, applies a constrained reasoning model operating under a strict output schema, and returns a structured biological signal report. The study evaluates the internal consistency of extracted signals, the calibration of confidence scores relative to dataset size and symptom specificity, and the distribution of biological signal categories across a large anonymous population. No intervention is assigned. No participant contact occurs. All data is anonymized at the point of collection.

CONDITIONS

Official Title

Biomedical Signal Extraction From Symptom Descriptions: An Observational Registry Using the OpenGenome Platform

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Submissions must be made voluntarily by adults aged 18 years or older
  • Symptom descriptions must be free-text and contain discernible symptom or health-related content
  • Submissions must not be automated or programmatically generated
  • All data must be anonymized at the point of collection
Not Eligible

You will not qualify if you...

  • Submissions that are automated or programmatically generated
  • Submissions without discernible symptom or health-related content

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

OpenGenome

Friedrichshain, State of Berlin, Germany, 10243

Actively Recruiting

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Research Team

R

Richard Koch

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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