Timing of diagnostic workups in Chinese population with recurrent pregnancy loss: a cross-sectional study.
Liyang Zhang, Yushu Du, Jingshuang Zhou...
https://pubmed.ncbi.nlm.nih.gov/40158174Actively Recruiting
Age: 18Years +
FEMALE
Healthy Volunteers
ID03561766
Birth Cohort Study of China Medical University in Shenyang
Led by Shengjing Hospital · Updated on 2019-12-12
1000
Participants Needed
1
Research Sites
887 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to understand how genes and environmental factors interact to influence the development of diseases. It focuses on pregnant women and their children from birth up to 18 years old, studying key health conditions like overweight and obesity in children. The study collects detailed lifestyle, family, clinical, and imaging data to explore the origins and long-term health impacts beginning in early life. Participants include pregnant women under 13 weeks of gestation living in Shenyang or nearby areas who plan to deliver at Shengjing Hospital. The study tracks biometric changes in fetuses weekly from the thirteenth week of pregnancy until birth, measures newborn weight, and analyzes gene expression in both mothers and their partners. It also monitors non-invasive prenatal testing results and collects biological samples from children and parents. Throughout the study, children are followed up to age 18 with periodic assessments of their intestinal flora, height, weight, and gene expression at multiple ages. Researchers collect various clinical data and biological samples during pregnancy and childhood to evaluate health outcomes. Participation involves ongoing data collection, clinical visits, and sample donations to monitor growth and development over many years.
CONDITIONS
Brief Title
Birth Cohort Study of China Medical University
Who Can Participate
Age: 18Years +
FEMALE
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Pregnant women less than 13 weeks gestational age
- Permanent residents or families planning to remain in Shenyang and surrounding areas
- Pregnant women planning to be examined and deliver at Shengjing Hospital
You will not qualify if you...
- Pregnant women who refuse to participate in the study
- Pregnant women with diseases that might affect research results, including neuropsychiatric disorders
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
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Your Study Journey
Screening
Duration - Up to 13 weeks of gestational age
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit
Diagnostic Evaluation
Duration - From 12 to 34 weeks of gestational age until delivery
Participants undergo assessments including biometric measurements and gene expression analyses during pregnancy.
Multiple visits during pregnancy including assessments at 13, 26, and 34 weeks of gestational age
Long-term Monitoring
Duration - Up to 18 years after birth
Participants and their children are followed over several years to monitor growth, gene expression changes, and intestinal flora development.
Assessments at ages 1, 3, 6, 9, 12, 15, and 18 years
Trial Site Locations
Total: 1 location
1
Shengjing Hospital
Shenyang, Liaoning, China, 110004
Actively Recruiting
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Research Team
C
Caixia Liu
S
Shaojiang Liu
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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