Actively Recruiting
Long-Term Study to Find Blood and Clinical Markers for Early Detection of Pancreas Cancer in High-Risk Adults
Led by University of Nebraska · Updated on 2026-02-02
1250
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are conducting a longitudinal study to identify early blood markers and clinical signs of pancreatic ductal adenocarcinoma PDAC, a form of pancreas cancer with a very low survival rate due to late diagnosis. The study focuses on people at higher than average risk, including those with family history, certain pancreas conditions, or new-onset diabetes, to improve early detection and outcomes. Participants are grouped based on risk factors new onset or high-risk pre-diabetes, pancreatic cystic lesions or chronic pancreatitis, and inherited genetic risks. The study involves collecting clinical data and banking blood samples over time to find biomarkers that may predict early pancreas cancer and related diabetes changes. Participants will attend in-person visits twice a year in Omaha, NE, for blood sample collection and clinical assessments. The study will track the number of pancreas cancer cases diagnosed, explore blood markers linked to early cancer, and evaluate tests indicating diabetes related to pancreas cancer risk over a 10-year period. This long-term observation aims to support earlier diagnosis and better management of PDAC.
CONDITIONS
Brief Title
Blood Markers of Early Pancreas Cancer
Research Team
S
Suzanne M Wessling, RN, BSN
K
Kelsey A Klute, MD
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