Actively Recruiting

Age: 19Years +
All Genders
Healthy Volunteers
NCT03568630

Blood Markers of Early Pancreas Cancer

Led by University of Nebraska · Updated on 2026-02-02

1250

Participants Needed

1

Research Sites

518 weeks

Total Duration

On this page

Sponsors

U

University of Nebraska

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Identifying biomarkers of early pancreatic ductal adenocarcinoma (PDAC) could facilitate screening for individuals at higher than average risk and expedite the diagnosis in individuals with symptoms and substantially improve an individual's chance of surviving the disease. The investigators propose a longitudinal study of subjects at higher than average risk of PDAC in order to generate clinical data and bank serial blood specimens.

CONDITIONS

Official Title

Blood Markers of Early Pancreas Cancer

Who Can Participate

Age: 19Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 19 years or older
  • Able to provide written, informed consent
  • Able to attend in-person study visits in Omaha, NE twice a year for blood sample collection
  • Meet criteria for at least one risk group: new onset type 2 diabetes diagnosed within past 3 years, high-risk pre-diabetes, pancreatic cystic neoplasm or chronic pancreatitis diagnosed by imaging or specialist, or inherited risk due to family history or specific genetic mutations
Not Eligible

You will not qualify if you...

  • Personal history of pancreatic ductal adenocarcinoma (PDAC)
  • Currently receiving treatment for cancer (except long-term hormonal therapy)
  • Pre-diabetes treated with metformin for 3 years or longer

AI-Screening

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Trial Site Locations

Total: 1 location

1

Unversity of Nebraska Medical Center

Omaha, Nebraska, United States, 68198

Actively Recruiting

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Research Team

S

Suzanne M Wessling, RN, BSN

CONTACT

K

Kelsey A Klute, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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